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Items: 1 to 20 of 28


The OncoAge Consortium: Linking Aging and Oncology from Bench to Bedside and Back Again.

Hofman P, Ayache N, Barbry P, Barlaud M, Bel A, Blancou P, Checler F, Chevillard S, Cristofari G, Demory M, Esnault V, Falandry C, Gilson E, Guérin O, Glaichenhaus N, Guigay J, Ilié M, Mari B, Marquette CH, Paquis-Flucklinger V, Prate F, Saintigny P, Seitz-Polsky B, Skhiri T, Van Obberghen-Schilling E, Van Obberghen E, Yvan-Charvet L.

Cancers (Basel). 2019 Feb 21;11(2). pii: E250. doi: 10.3390/cancers11020250.


Nanometric axial resolution of fibronectin assembly units achieved with an efficient reconstruction approach for multi-angle-TIRF microscopy.

Soubies E, Radwanska A, Grall D, Blanc-Féraud L, Van Obberghen-Schilling E, Schaub S.

Sci Rep. 2019 Feb 13;9(1):1926. doi: 10.1038/s41598-018-36119-3.


Counterbalancing anti-adhesive effects of Tenascin-C through fibronectin expression in endothelial cells.

Radwanska A, Grall D, Schaub S, Divonne SBF, Ciais D, Rekima S, Rupp T, Sudaka A, Orend G, Van Obberghen-Schilling E.

Sci Rep. 2017 Oct 6;7(1):12762. doi: 10.1038/s41598-017-13008-9.


Unique DNA methylation signature in HPV-positive head and neck squamous cell carcinomas.

Degli Esposti D, Sklias A, Lima SC, Beghelli-de la Forest Divonne S, Cahais V, Fernandez-Jimenez N, Cros MP, Ecsedi S, Cuenin C, Bouaoun L, Byrnes G, Accardi R, Sudaka A, Giordanengo V, Hernandez-Vargas H, Pinto LF, Van Obberghen-Schilling E, Herceg Z.

Genome Med. 2017 Apr 5;9(1):33. doi: 10.1186/s13073-017-0419-z.


Fibronectin-guided migration of carcinoma collectives.

Gopal S, Veracini L, Grall D, Butori C, Schaub S, Audebert S, Camoin L, Baudelet E, Radwanska A, Beghelli-de la Forest Divonne S, Violette SM, Weinreb PH, Rekima S, Ilie M, Sudaka A, Hofman P, Van Obberghen-Schilling E.

Nat Commun. 2017 Jan 19;8:14105. doi: 10.1038/ncomms14105.


Tenascin-C Orchestrates Glioblastoma Angiogenesis by Modulation of Pro- and Anti-angiogenic Signaling.

Rupp T, Langlois B, Koczorowska MM, Radwanska A, Sun Z, Hussenet T, Lefebvre O, Murdamoothoo D, Arnold C, Klein A, Biniossek ML, Hyenne V, Naudin E, Velazquez-Quesada I, Schilling O, Van Obberghen-Schilling E, Orend G.

Cell Rep. 2016 Dec 6;17(10):2607-2619. doi: 10.1016/j.celrep.2016.11.012.


A Positive Feed-forward Loop Associating EGR1 and PDGFA Promotes Proliferation and Self-renewal in Glioblastoma Stem Cells.

Sakakini N, Turchi L, Bergon A, Holota H, Rekima S, Lopez F, Paquis P, Almairac F, Fontaine D, Baeza-Kallee N, Van Obberghen-Schilling E, Junier MP, Chneiweiss H, Figarella-Branger D, Burel-Vandenbos F, Imbert J, Virolle T.

J Biol Chem. 2016 May 13;291(20):10684-99. doi: 10.1074/jbc.M116.720698. Epub 2016 Mar 21.


Integrating genomics in head and neck cancer treatment: Promises and pitfalls.

Thariat J, Vignot S, Lapierre A, Falk AT, Guigay J, Van Obberghen-Schilling E, Milano G.

Crit Rev Oncol Hematol. 2015 Sep;95(3):397-406. doi: 10.1016/j.critrevonc.2015.03.005. Epub 2015 Apr 18. Review.


Elevated Src family kinase activity stabilizes E-cadherin-based junctions and collective movement of head and neck squamous cell carcinomas.

Veracini L, Grall D, Schaub S, Beghelli-de la Forest Divonne S, Etienne-Grimaldi MC, Milano G, Bozec A, Babin E, Sudaka A, Thariat J, Van Obberghen-Schilling E.

Oncotarget. 2015 Apr 10;6(10):7570-83.


Tumorigenic potential of miR-18A* in glioma initiating cells requires NOTCH-1 signaling.

Turchi L, Debruyne DN, Almairac F, Virolle V, Fareh M, Neirijnck Y, Burel-Vandenbos F, Paquis P, Junier MP, Van Obberghen-Schilling E, Chneiweiss H, Virolle T.

Stem Cells. 2013 Jul;31(7):1252-65. doi: 10.1002/stem.1373.


Contrasted outcomes to gefitinib on tumoral IGF1R expression in head and neck cancer patients receiving postoperative chemoradiation (GORTEC trial 2004-02).

Thariat J, Bensadoun RJ, Etienne-Grimaldi MC, Grall D, Penault-Llorca F, Dassonville O, Bertucci F, Cayre A, De Raucourt D, Geoffrois L, Finetti P, Giraud P, Racadot S, Morinière S, Sudaka A, Van Obberghen-Schilling E, Milano G.

Clin Cancer Res. 2012 Sep 15;18(18):5123-33. Epub 2012 Aug 1.


Epidermal growth factor receptor protein detection in head and neck cancer patients: a many-faceted picture.

Thariat J, Etienne-Grimaldi MC, Grall D, Bensadoun RJ, Cayre A, Penault-Llorca F, Veracini L, Francoual M, Formento JL, Dassonville O, De Raucourt D, Geoffrois L, Giraud P, Racadot S, Morinière S, Milano G, Van Obberghen-Schilling E.

Clin Cancer Res. 2012 Mar 1;18(5):1313-22. doi: 10.1158/1078-0432.CCR-11-2339. Epub 2012 Jan 6.


Fibronectin and tenascin-C: accomplices in vascular morphogenesis during development and tumor growth.

Van Obberghen-Schilling E, Tucker RP, Saupe F, Gasser I, Cseh B, Orend G.

Int J Dev Biol. 2011;55(4-5):511-25. doi: 10.1387/ijdb.103243eo. Review.


Raf-1 activation prevents caspase 9 processing downstream of apoptosome formation.

Cagnol S, Mansour A, Van Obberghen-Schilling E, Chambard JC.

J Signal Transduct. 2011;2011:834948. doi: 10.1155/2011/834948. Epub 2010 Oct 14.


Autocrine fibronectin directs matrix assembly and crosstalk between cell-matrix and cell-cell adhesion in vascular endothelial cells.

Cseh B, Fernandez-Sauze S, Grall D, Schaub S, Doma E, Van Obberghen-Schilling E.

J Cell Sci. 2010 Nov 15;123(Pt 22):3989-99. doi: 10.1242/jcs.073346. Epub 2010 Oct 27.


Molecular dissection of the ILK-PINCH-parvin triad reveals a fundamental role for the ILK kinase domain in the late stages of focal-adhesion maturation.

Stanchi F, Grashoff C, Nguemeni Yonga CF, Grall D, Fässler R, Van Obberghen-Schilling E.

J Cell Sci. 2009 Jun 1;122(Pt 11):1800-11. doi: 10.1242/jcs.044602. Epub 2009 May 12.


Regulation of fibronectin matrix assembly and capillary morphogenesis in endothelial cells by Rho family GTPases.

Fernandez-Sauze S, Grall D, Cseh B, Van Obberghen-Schilling E.

Exp Cell Res. 2009 Jul 15;315(12):2092-104. doi: 10.1016/j.yexcr.2009.03.017. Epub 2009 Mar 28.


Overexpression of cortactin in head and neck squamous cell carcinomas can be uncoupled from augmented EGF receptor expression.

Fantozzi I, Grall D, Cagnol S, Stanchi F, Sudaka A, Brunstein MC, Bozec A, Fischel JL, Milano G, Van Obberghen-Schilling E.

Acta Oncol. 2008;47(8):1502-12. doi: 10.1080/02841860802089801.


Pituicyte stellation is prevented by RhoA-or Cdc42-dependent actin polymerization.

Rosso L, Pierson PM, Golfier C, Peteri-Brunbäck B, Deroanne C, Van Obberghen-Schilling E, Mienville JM.

Cell Mol Neurobiol. 2007 Sep;27(6):791-804. Epub 2007 Aug 22.


Blockade of alpha v beta3 and alpha v beta5 integrins by RGD mimetics induces anoikis and not integrin-mediated death in human endothelial cells.

Maubant S, Saint-Dizier D, Boutillon M, Perron-Sierra F, Casara PJ, Hickman JA, Tucker GC, Van Obberghen-Schilling E.

Blood. 2006 Nov 1;108(9):3035-44. Epub 2006 Jul 11.

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