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Next-Generation Hedgehog/GLI Pathway Inhibitors for Cancer Therapy.

Peer E, Tesanovic S, Aberger F.

Cancers (Basel). 2019 Apr 15;11(4). pii: E538. doi: 10.3390/cancers11040538. Review.


Targeting class I histone deacetylases by the novel small molecule inhibitor 4SC-202 blocks oncogenic hedgehog-GLI signaling and overcomes smoothened inhibitor resistance.

Gruber W, Peer E, Elmer DP, Sternberg C, Tesanovic S, Del Burgo P, Coni S, Canettieri G, Neureiter D, Bartz R, Kohlhof H, Vitt D, Aberger F.

Int J Cancer. 2018 Mar 1;142(5):968-975. doi: 10.1002/ijc.31117. Epub 2017 Nov 6.

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