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Items: 1 to 20 of 23

1.

Understanding the role of distance, direction and cue salience in an associative model of landmark learning.

Commins S, Fey D.

Sci Rep. 2019 Feb 14;9(1):2026. doi: 10.1038/s41598-019-38525-7.

2.

Impact of measurement noise, experimental design, and estimation methods on Modular Response Analysis based network reconstruction.

Thomaseth C, Fey D, Santra T, Rukhlenko OS, Radde NE, Kholodenko BN.

Sci Rep. 2018 Nov 1;8(1):16217. doi: 10.1038/s41598-018-34353-3.

3.

Systems biology: old news or new stimulus for biochemistry.

Kolch W, Fey D, Ryan CJ.

Essays Biochem. 2018 Oct 26;62(4):483-486. doi: 10.1042/EBC20180002. Print 2018 Oct 26.

PMID:
30366987
4.

MASTL overexpression promotes chromosome instability and metastasis in breast cancer.

Rogers S, McCloy RA, Parker BL, Gallego-Ortega D, Law AMK, Chin VT, Conway JRW, Fey D, Millar EKA, O'Toole S, Deng N, Swarbrick A, Chastain PD, Cesare AJ, Timpson P, Caldon CE, Croucher DR, James DE, Watkins DN, Burgess A.

Oncogene. 2018 Aug;37(33):4518-4533. doi: 10.1038/s41388-018-0295-z. Epub 2018 May 10.

5.

The extracellular matrix as a key regulator of intracellular signalling networks.

Hastings JF, Skhinas JN, Fey D, Croucher DR, Cox TR.

Br J Pharmacol. 2019 Jan;176(1):82-92. doi: 10.1111/bph.14195. Epub 2018 Apr 19. Review.

PMID:
29510460
6.

Personalized Computational Models as Biomarkers.

Kolch W, Fey D.

J Pers Med. 2017 Sep 1;7(3). pii: E9. doi: 10.3390/jpm7030009.

7.

Performance of objective functions and optimisation procedures for parameter estimation in system biology models.

Degasperi A, Fey D, Kholodenko BN.

NPJ Syst Biol Appl. 2017 Aug 8;3:20. doi: 10.1038/s41540-017-0023-2. eCollection 2017.

8.

Modeling of Receptor Tyrosine Kinase Signaling: Computational and Experimental Protocols.

Fey D, Aksamitiene E, Kiyatkin A, Kholodenko BN.

Methods Mol Biol. 2017;1636:417-453. doi: 10.1007/978-1-4939-7154-1_27.

PMID:
28730495
9.

Wnt signalling is a bi-directional vulnerability of cancer cells.

Duffy DJ, Krstic A, Schwarzl T, Halasz M, Iljin K, Fey D, Haley B, Whilde J, Haapa-Paananen S, Fey V, Fischer M, Westermann F, Henrich KO, Bannert S, Higgins DG, Kolch W.

Oncotarget. 2016 Sep 13;7(37):60310-60331. doi: 10.18632/oncotarget.11203.

10.

The complexities and versatility of the RAS-to-ERK signalling system in normal and cancer cells.

Fey D, Matallanas D, Rauch J, Rukhlenko OS, Kholodenko BN.

Semin Cell Dev Biol. 2016 Oct;58:96-107. doi: 10.1016/j.semcdb.2016.06.011. Epub 2016 Jun 24. Review.

PMID:
27350026
11.

Frequency modulation of ERK activation dynamics rewires cell fate.

Ryu H, Chung M, Dobrzyński M, Fey D, Blum Y, Sik Lee S, Peter M, Kholodenko BN, Li Jeon N, Pertz O.

Mol Syst Biol. 2016 Apr 22;12(4):866. doi: 10.15252/msb.20166982. No abstract available.

12.

PP1 initiates the dephosphorylation of MASTL, triggering mitotic exit and bistability in human cells.

Rogers S, Fey D, McCloy RA, Parker BL, Mitchell NJ, Payne RJ, Daly RJ, James DE, Caldon CE, Watkins DN, Croucher DR, Burgess A.

J Cell Sci. 2016 Apr 1;129(7):1340-54. doi: 10.1242/jcs.179754. Epub 2016 Feb 12.

13.

Signaling pathway models as biomarkers: Patient-specific simulations of JNK activity predict the survival of neuroblastoma patients.

Fey D, Halasz M, Dreidax D, Kennedy SP, Hastings JF, Rauch N, Munoz AG, Pilkington R, Fischer M, Westermann F, Kolch W, Kholodenko BN, Croucher DR.

Sci Signal. 2015 Dec 22;8(408):ra130. doi: 10.1126/scisignal.aab0990.

PMID:
26696630
14.

Integrative omics reveals MYCN as a global suppressor of cellular signalling and enables network-based therapeutic target discovery in neuroblastoma.

Duffy DJ, Krstic A, Halasz M, Schwarzl T, Fey D, Iljin K, Mehta JP, Killick K, Whilde J, Turriziani B, Haapa-Paananen S, Fey V, Fischer M, Westermann F, Henrich KO, Bannert S, Higgins DG, Kolch W.

Oncotarget. 2015 Dec 22;6(41):43182-201. doi: 10.18632/oncotarget.6568.

15.

Frequency modulation of ERK activation dynamics rewires cell fate.

Ryu H, Chung M, Dobrzyński M, Fey D, Blum Y, Lee SS, Peter M, Kholodenko BN, Jeon NL, Pertz O.

Mol Syst Biol. 2015 Nov 27;11(11):838. doi: 10.15252/msb.20156458. Erratum in: Mol Syst Biol. 2016 Apr;12(4):866.

16.

Multiscale model of dynamic neuromodulation integrating neuropeptide-induced signaling pathway activity with membrane electrophysiology.

Makadia HK, Anderson WD, Fey D, Sauter T, Schwaber JS, Vadigepalli R.

Biophys J. 2015 Jan 6;108(1):211-23. doi: 10.1016/j.bpj.2014.11.1851.

17.

Polyubiquitin chain assembly and organization determine the dynamics of protein activation and degradation.

Nguyen LK, Dobrzyński M, Fey D, Kholodenko BN.

Front Physiol. 2014 Jan 24;5:4. doi: 10.3389/fphys.2014.00004. eCollection 2014.

18.

Control of the G-protein cascade dynamics by GDP dissociation inhibitors.

Nikonova E, Tsyganov MA, Kolch W, Fey D, Kholodenko BN.

Mol Biosyst. 2013 Oct;9(10):2454-62. doi: 10.1039/c3mb70152b.

PMID:
23872884
19.

Pseudophosphatase STYX modulates cell-fate decisions and cell migration by spatiotemporal regulation of ERK1/2.

Reiterer V, Fey D, Kolch W, Kholodenko BN, Farhan H.

Proc Natl Acad Sci U S A. 2013 Jul 30;110(31):E2934-43. doi: 10.1073/pnas.1301985110. Epub 2013 Jul 11.

20.

Hippocampal contribution to vector model hypothesis during cue-dependent navigation.

Diviney M, Fey D, Commins S.

Learn Mem. 2013 Jun 17;20(7):367-78. doi: 10.1101/lm.029272.112.

PMID:
23774767

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