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Items: 1 to 20 of 80

1.

New heterobimetallic ferrocenyl derivatives are promising antitrypanosomal agents.

Rodríguez Arce E, Putzu E, Lapier M, Maya JD, Olea Azar C, Echeverría GA, Piro OE, Medeiros A, Sardi F, Comini M, Risi G, Salinas G, Correia I, Pessoa JC, Otero L, Gambino D.

Dalton Trans. 2019 May 3. doi: 10.1039/c9dt01317b. [Epub ahead of print]

PMID:
31049548
2.

Antioxidant Nanomaterial Based on Core⁻Shell Silica Nanospheres with Surface-Bound Caffeic Acid: A Promising Vehicle for Oxidation-Sensitive Drugs.

Arriagada F, Günther G, Nos J, Nonell S, Olea-Azar C, Morales J.

Nanomaterials (Basel). 2019 Feb 6;9(2). pii: E214. doi: 10.3390/nano9020214.

3.

Targeting α -(1,4)-Glucosidase in Diabetes Mellitus Type 2: The Role of New Synthetic Coumarins as Potent Inhibitors.

Figueroa-Benavides C, Matos MJ, Peñaloza-Amion M, Veas R, Valenzuela-Barra G, Zapata G, Delogu G, Uriarte E, Santana L, Olea-Azar C, Delporte C.

Curr Top Med Chem. 2018;18(27):2327-2337. doi: 10.2174/1568026619666181130113033.

PMID:
30499400
4.

Evaluation of Trypanocidal and Antioxidant Activities of a Selected Series of 3-amidocoumarins.

Moncada-Basualto M, Lapier M, Maya JD, Matsuhiro B, Olea-Azar C, Delogu GL, Uriarte E, Santana L, Matos MJ.

Med Chem. 2018;14(6):573-584. doi: 10.2174/1573406414666180419113437.

PMID:
29669503
5.

Ibandronate metal complexes: solution behavior and antiparasitic activity.

Demoro B, Rostán S, Moncada M, Li ZH, Docampo R, Olea Azar C, Maya JD, Torres J, Gambino D, Otero L.

J Biol Inorg Chem. 2018 Mar;23(2):303-312. doi: 10.1007/s00775-018-1535-y. Epub 2018 Jan 18.

PMID:
29349663
6.

Rhenium(I) tricarbonyl compounds of bioactive thiosemicarbazones: Synthesis, characterization and activity against Trypanosoma cruzi.

Rodríguez Arce E, Machado I, Rodríguez B, Lapier M, Zúñiga MC, Maya JD, Olea Azar C, Otero L, Gambino D.

J Inorg Biochem. 2017 May;170:125-133. doi: 10.1016/j.jinorgbio.2017.01.011. Epub 2017 Jan 23.

PMID:
28237731
7.

Synthesis, antioxidant and antichagasic properties of a selected series of hydroxy-3-arylcoumarins.

Robledo-O'Ryan N, Matos MJ, Vazquez-Rodriguez S, Santana L, Uriarte E, Moncada-Basualto M, Mura F, Lapier M, Maya JD, Olea-Azar C.

Bioorg Med Chem. 2017 Jan 15;25(2):621-632. doi: 10.1016/j.bmc.2016.11.033. Epub 2016 Nov 19.

PMID:
27908757
8.

Morin Flavonoid Adsorbed on Mesoporous Silica, a Novel Antioxidant Nanomaterial.

Arriagada F, Correa O, Günther G, Nonell S, Mura F, Olea-Azar C, Morales J.

PLoS One. 2016 Nov 3;11(11):e0164507. doi: 10.1371/journal.pone.0164507. eCollection 2016.

9.

Evaluation of the Novel Antichagasic Activity of [1,2,3]Triazolo[1,5-a]pyridine Derivatives.

Lapier M, Zuniga-Lopez MC, Aguilera-Venegas B, Adam R, Abarca B, Ballesteros R, Lopez-Munoz R, Maya JD, Olea-Azar C.

Curr Top Med Chem. 2017;17(4):399-411.

PMID:
27558681
10.

Facing Chagas' disease: trypanocidal properties of new coumarin-chalcone scaffolds.

Vazquez-Rodriguez S, Guíñez RF, Matos MJ, Olea-Azar C, Maya JD, Uriarte E, Santana L.

Med Chem. 2016 Jan 6. [Epub ahead of print]

PMID:
26740208
11.

Novel ruthenium(II) cyclopentadienyl thiosemicarbazone compounds with antiproliferative activity on pathogenic trypanosomatid parasites.

Fernández M, Arce ER, Sarniguet C, Morais TS, Tomaz AI, Azar CO, Figueroa R, Diego Maya J, Medeiros A, Comini M, Helena Garcia M, Otero L, Gambino D.

J Inorg Biochem. 2015 Dec;153:306-314. doi: 10.1016/j.jinorgbio.2015.06.018. Epub 2015 Jun 30.

PMID:
26275470
12.

Interest of antioxidant agents in parasitic diseases. The case study of coumarins.

Figueroa-Guiñez R, Matos MJ, Vazquez-Rodriguez S, Santana L, Uriarte E, Borges F, Olea-Azar C, Maya JD.

Curr Top Med Chem. 2015;15(9):850-6. Review.

PMID:
25697564
13.

Study of coumarin-resveratrol hybrids as potent antioxidant compounds.

Matos MJ, Mura F, Vazquez-Rodriguez S, Borges F, Santana L, Uriarte E, Olea-Azar C.

Molecules. 2015 Feb 16;20(2):3290-308. doi: 10.3390/molecules20023290.

14.

Spin trapping: an essential tool for the study of diseases caused by oxidative stress.

Barriga-González G, Olea-Azar C, Zuñiga-López MC, Folch-Cano C, Aguilera-Venegas B, Porcal W, González M, Cerecetto H.

Curr Top Med Chem. 2015;15(5):484-95. Review.

PMID:
25658802
15.

Inclusion and functionalization of polymers with cyclodextrins: current applications and future prospects.

Folch-Cano C, Yazdani-Pedram M, Olea-Azar C.

Molecules. 2014 Sep 9;19(9):14066-79. doi: 10.3390/molecules190914066. Review.

16.

Water-soluble ruthenium complexes bearing activity against protozoan parasites.

Sarniguet C, Toloza J, Cipriani M, Lapier M, Vieites M, Toledano-Magaña Y, García-Ramos JC, Ruiz-Azuara L, Moreno V, Maya JD, Azar CO, Gambino D, Otero L.

Biol Trace Elem Res. 2014 Jun;159(1-3):379-92. doi: 10.1007/s12011-014-9964-0. Epub 2014 Apr 17.

PMID:
24740394
17.

Synthesis and evaluation of antioxidant and trypanocidal properties of a selected series of coumarin derivatives.

Guíñez RF, Matos MJ, Vazquez-Rodriguez S, Santana L, Uriarte E, Olea-Azar C, Maya JD.

Future Med Chem. 2013 Oct;5(16):1911-22. doi: 10.4155/fmc.13.147.

PMID:
24175743
18.

Indazoles: a new top seed structure in the search of efficient drugs against Trypanosoma cruzi.

Aguilera-Venegas B, Olea-Azar C, Arán VJ, Speisky H.

Future Med Chem. 2013 Oct;5(15):1843-59. doi: 10.4155/fmc.13.144. Review.

PMID:
24144415
19.

Synthetic cannabinoid quinones: preparation, in vitro antiproliferative effects and in vivo prostate antitumor activity.

Morales P, Vara D, Goméz-Cañas M, Zúñiga MC, Olea-Azar C, Goya P, Fernández-Ruiz J, Díaz-Laviada I, Jagerovic N.

Eur J Med Chem. 2013;70:111-9. doi: 10.1016/j.ejmech.2013.09.043. Epub 2013 Oct 2.

PMID:
24141201
20.

Synthesis and electrochemical and biological studies of novel coumarin-chalcone hybrid compounds.

Pérez-Cruz F, Vazquez-Rodriguez S, Matos MJ, Herrera-Morales A, Villamena FA, Das A, Gopalakrishnan B, Olea-Azar C, Santana L, Uriarte E.

J Med Chem. 2013 Aug 8;56(15):6136-45. doi: 10.1021/jm400546y. Epub 2013 Jul 30.

PMID:
23859213

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