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Items: 1 to 20 of 27

1.

Using Nanospray Liquid Chromatography and Mass Spectrometry to Quantitate Shiga Toxin Production in Environmental Escherichia coli Recovered from a Major Produce Production Region in California.

Silva CJ, Lee BG, Yambao JC, Erickson-Beltran ML, Quiñones B.

J Agric Food Chem. 2019 Feb 6;67(5):1554-1562. doi: 10.1021/acs.jafc.8b05324. Epub 2018 Dec 21.

PMID:
30485086
2.

Food Forensics: Using Mass Spectrometry To Detect Foodborne Protein Contaminants, as Exemplified by Shiga Toxin Variants and Prion Strains.

Silva CJ.

J Agric Food Chem. 2018 Aug 15;66(32):8435-8450. doi: 10.1021/acs.jafc.8b01517. Epub 2018 Jun 13. Review.

PMID:
29860833
3.

Recombinant PrPSc shares structural features with brain-derived PrPSc: Insights from limited proteolysis.

Sevillano AM, Fernández-Borges N, Younas N, Wang F, R Elezgarai S, Bravo S, Vázquez-Fernández E, Rosa I, Eraña H, Gil D, Veiga S, Vidal E, Erickson-Beltran ML, Guitián E, Silva CJ, Nonno R, Ma J, Castilla J, R Requena J.

PLoS Pathog. 2018 Jan 31;14(1):e1006797. doi: 10.1371/journal.ppat.1006797. eCollection 2018 Jan.

4.

An Improved Method for the Sensitive Detection of Shiga Toxin 2 in Human Serum.

He X, Ardissino G, Patfield S, Cheng LW, Silva CJ, Brigotti M.

Toxins (Basel). 2018 Jan 31;10(2). pii: E59. doi: 10.3390/toxins10020059.

5.

Determining the Relative Susceptibility of Four Prion Protein Genotypes to Atypical Scrapie.

Silva CJ, Erickson-Beltran ML, Martín-Burriel I, Badiola JJ, Requena JR, Bolea R.

Anal Chem. 2018 Jan 16;90(2):1255-1262. doi: 10.1021/acs.analchem.7b03985. Epub 2018 Jan 2.

PMID:
29240410
6.

Quantitating PrP Polymorphisms Present in Prions from Heterozygous Scrapie-Infected Sheep.

Silva CJ, Erickson-Beltran ML, Hui C, Badiola JJ, Nicholson EM, Requena JR, Bolea R.

Anal Chem. 2017 Jan 3;89(1):854-861. doi: 10.1021/acs.analchem.6b03822. Epub 2016 Dec 21.

PMID:
27936597
7.

Identification of new molecular alterations in fatal familial insomnia.

Llorens F, Thüne K, Schmitz M, Ansoleaga B, Frau-Méndez MA, Cramm M, Tahir W, Gotzmann N, Berjaoui S, Carmona M, Silva CJ, Fernandez-Vega I, José Zarranz J, Zerr I, Ferrer I.

Hum Mol Genet. 2016 Jun 15;25(12):2417-2436. Epub 2016 Apr 7.

PMID:
27056979
8.

Covalent Surface Modification of Prions: A Mass Spectrometry-Based Means of Detecting Distinctive Structural Features of Prion Strains.

Silva CJ, Erickson-Beltran ML, Dynin IC.

Biochemistry. 2016 Feb 16;55(6):894-902. doi: 10.1021/acs.biochem.5b01068. Epub 2016 Feb 2.

PMID:
26786805
9.

Mass Spectrometry-Based Method of Detecting and Distinguishing Type 1 and Type 2 Shiga-Like Toxins in Human Serum.

Silva CJ, Erickson-Beltran ML, Skinner CB, Patfield SA, He X.

Toxins (Basel). 2015 Dec 2;7(12):5236-53. doi: 10.3390/toxins7124875.

10.

Proteinase K and the structure of PrPSc: The good, the bad and the ugly.

Silva CJ, Vázquez-Fernández E, Onisko B, Requena JR.

Virus Res. 2015 Sep 2;207:120-6. doi: 10.1016/j.virusres.2015.03.008. Epub 2015 Mar 24. Review.

PMID:
25816779
11.

Behavioral abnormalities in prion protein knockout mice and the potential relevance of PrP(C) for the cytoskeleton.

Schmitz M, Zafar S, Silva CJ, Zerr I.

Prion. 2014;8(6):381-6. doi: 10.4161/19336896.2014.983746.

12.

Safe and effective means of detecting and quantitating Shiga-like toxins in attomole amounts.

Silva CJ, Erickson-Beltran ML, Skinner CB, Dynin I, Hui C, Patfield SA, Carter JM, He X.

Anal Chem. 2014 May 20;86(10):4698-706. doi: 10.1021/ac402930r. Epub 2014 May 2.

PMID:
24761992
13.

Loss of prion protein leads to age-dependent behavioral abnormalities and changes in cytoskeletal protein expression.

Schmitz M, Greis C, Ottis P, Silva CJ, Schulz-Schaeffer WJ, Wrede A, Koppe K, Onisko B, Requena JR, Govindarajan N, Korth C, Fischer A, Zerr I.

Mol Neurobiol. 2014 Dec;50(3):923-36. doi: 10.1007/s12035-014-8655-3. Epub 2014 Mar 7.

PMID:
24604355
15.

Oxidation of methionine 216 in sheep and elk prion protein is highly dependent upon the amino acid at position 218 but is not important for prion propagation.

Silva CJ, Dynin I, Erickson ML, Requena JR, Balachandran A, Hui C, Onisko BC, Carter JM.

Biochemistry. 2013 Mar 26;52(12):2139-47. doi: 10.1021/bi3016795. Epub 2013 Mar 15.

PMID:
23458153
16.

Structural organization of mammalian prions as probed by limited proteolysis.

Vázquez-Fernández E, Alonso J, Pastrana MA, Ramos A, Stitz L, Vidal E, Dynin I, Petsch B, Silva CJ, Requena JR.

PLoS One. 2012;7(11):e50111. doi: 10.1371/journal.pone.0050111. Epub 2012 Nov 20.

17.

Human and rat brain lipofuscin proteome.

Ottis P, Koppe K, Onisko B, Dynin I, Arzberger T, Kretzschmar H, Requena JR, Silva CJ, Huston JP, Korth C.

Proteomics. 2012 Aug;12(15-16):2445-54. doi: 10.1002/pmic.201100668.

PMID:
22707227
18.

Using small molecule reagents to selectively modify epitopes based on their conformation.

Silva CJ.

Prion. 2012 Apr-Jun;6(2):163-73. doi: 10.4161/pri.18795. Epub 2012 Apr 1.

19.

PK-sensitive PrP is infectious and shares basic structural features with PK-resistant PrP.

Sajnani G, Silva CJ, Ramos A, Pastrana MA, Onisko BC, Erickson ML, Antaki EM, Dynin I, Vázquez-Fernández E, Sigurdson CJ, Carter JM, Requena JR.

PLoS Pathog. 2012;8(3):e1002547. doi: 10.1371/journal.ppat.1002547. Epub 2012 Mar 1.

20.

Probing structural differences between PrP(C) and PrP(Sc) by surface nitration and acetylation: evidence of conformational change in the C-terminus.

Gong B, Ramos A, Vázquez-Fernández E, Silva CJ, Alonso J, Liu Z, Requena JR.

Biochemistry. 2011 Jun 7;50(22):4963-72. doi: 10.1021/bi102073j. Epub 2011 May 11.

PMID:
21526750

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