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Items: 1 to 20 of 422

1.

Elevated CTRP1 Plasma Concentration Is Associated with Sepsis and Pre-Existing Type 2 Diabetes Mellitus in Critically Ill Patients.

Yagmur E, Buergerhausen D, Koek GH, Weiskirchen R, Trautwein C, Koch A, Tacke F.

J Clin Med. 2019 May 11;8(5). pii: E661. doi: 10.3390/jcm8050661.

2.

Myeloid cells in liver and bone marrow acquire a functionally distinct inflammatory phenotype during obesity-related steatohepatitis.

Krenkel O, Hundertmark J, Abdallah AT, Kohlhepp M, Puengel T, Roth T, Branco DPP, Mossanen JC, Luedde T, Trautwein C, Costa IG, Tacke F.

Gut. 2019 May 10. pii: gutjnl-2019-318382. doi: 10.1136/gutjnl-2019-318382. [Epub ahead of print]

PMID:
31076404
3.

Neutrophils are a main source of circulating suPAR predicting outcome in critical illness.

Gussen H, Hohlstein P, Bartneck M, Warzecha KT, Buendgens L, Luedde T, Trautwein C, Koch A, Tacke F.

J Intensive Care. 2019 Apr 27;7:26. doi: 10.1186/s40560-019-0381-5. eCollection 2019.

4.

Platelet Factor 4 Attenuates Experimental Acute Liver Injury in Mice.

Drescher HK, Brandt EF, Fischer P, Dreschers S, Schwendener RA, Kowalska MA, Canbay A, Wasmuth HE, Weiskirchen R, Trautwein C, Berres ML, Kroy DC, Sahin H.

Front Physiol. 2019 Mar 26;10:326. doi: 10.3389/fphys.2019.00326. eCollection 2019.

5.

The Inhibitory T Cell Receptors PD1 and 2B4 Are Differentially Regulated on CD4 and CD8 T Cells in a Mouse Model of Non-alcoholic Steatohepatitis.

Hansel C, Erschfeld S, Baues M, Lammers T, Weiskirchen R, Trautwein C, Kroy DC, Drescher HK.

Front Pharmacol. 2019 Mar 13;10:244. doi: 10.3389/fphar.2019.00244. eCollection 2019.

6.

Liver fibrosis affects the targeting properties of drug delivery systems to macrophage subsets in vivo.

Ergen C, Niemietz PM, Heymann F, Baues M, Gremse F, Pola R, van Bloois L, Storm G, Kiessling F, Trautwein C, Luedde T, Lammers T, Tacke F.

Biomaterials. 2019 Jun;206:49-60. doi: 10.1016/j.biomaterials.2019.03.025. Epub 2019 Mar 22.

PMID:
30925288
7.

miR-155 Predicts Long-Term Mortality in Critically Ill Patients Younger than 65 Years.

Tacke F, Spehlmann ME, Vucur M, Benz F, Luedde M, Cardenas DV, Roy S, Loosen S, Hippe HJ, Frey N, Trautwein C, Koch A, Roderburg C, Luedde T.

Mediators Inflamm. 2019 Feb 24;2019:6714080. doi: 10.1155/2019/6714080. eCollection 2019.

8.

Intestinal dysbiosis augments liver disease progression via NLRP3 in a murine model of primary sclerosing cholangitis.

Liao L, Schneider KM, Galvez EJC, Frissen M, Marschall HU, Su H, Hatting M, Wahlström A, Haybaeck J, Puchas P, Mohs A, Peng J, Bergheim I, Nier A, Hennings J, Reißing J, Zimmermann HW, Longerich T, Strowig T, Liedtke C, Cubero FJ, Trautwein C.

Gut. 2019 Mar 14. pii: gutjnl-2018-316670. doi: 10.1136/gutjnl-2018-316670. [Epub ahead of print]

PMID:
30872395
9.

Prognostic Relevance of Altered Lymphocyte Subpopulations in Critical Illness and Sepsis.

Hohlstein P, Gussen H, Bartneck M, Warzecha KT, Roderburg C, Buendgens L, Trautwein C, Koch A, Tacke F.

J Clin Med. 2019 Mar 12;8(3). pii: E353. doi: 10.3390/jcm8030353.

10.

Nrf2 ameliorates DDC-induced sclerosing cholangitis and biliary fibrosis and improves the regenerative capacity of the liver.

Fragoulis A, Schenkel J, Herzog M, Schellenberg T, Jahr H, Pufe T, Trautwein C, Kensler TW, Streetz KL, Wruck CJ.

Toxicol Sci. 2019 Mar 2. pii: kfz055. doi: 10.1093/toxsci/kfz055. [Epub ahead of print]

PMID:
30825315
11.

High baseline soluble urokinase plasminogen activator receptor (suPAR) serum levels indicate adverse outcome after resection of pancreatic adenocarcinoma.

Loosen SH, Tacke F, Püthe N, Binneboesel M, Wiltberger G, Alizai PH, Kather JN, Paffenholz P, Ritz T, Koch A, Bergmann F, Trautwein C, Longerich T, Roderburg C, Neumann UP, Luedde T.

Carcinogenesis. 2019 Feb 26. pii: bgz033. doi: 10.1093/carcin/bgz033. [Epub ahead of print]

PMID:
30805627
12.

MyD88-dependent signaling in non-parenchymal cells promotes liver carcinogenesis.

Mohs A, Kuttkat N, Otto T, Youssef SA, De Bruin A, Trautwein C.

Carcinogenesis. 2019 Feb 13. pii: bgy173. doi: 10.1093/carcin/bgy173. [Epub ahead of print]

PMID:
30770929
13.

Disruption of the FasL/Fas axis protects against inflammation-derived tumorigenesis in chronic liver disease.

Cubero FJ, Woitok MM, Zoubek ME, de Bruin A, Hatting M, Trautwein C.

Cell Death Dis. 2019 Feb 8;10(2):115. doi: 10.1038/s41419-019-1391-x.

14.

Elevated serum levels of bone sialoprotein (BSP) predict long-term mortality in patients with pancreatic adenocarcinoma.

Loosen SH, Hoening P, Puethe N, Luedde M, Spehlmann M, Ulmer TF, Cardenas DV, Roy S, Tacke F, Trautwein C, Neumann UP, Luedde T, Roderburg C.

Sci Rep. 2019 Feb 6;9(1):1489. doi: 10.1038/s41598-018-38352-2.

15.

Myeloid cells require gp130 signaling for protective anti-inflammatory functions during sepsis.

Sackett SD, Otto T, Mohs A, Sander LE, Strauch S, Streetz KL, Kroy DC, Trautwein C.

FASEB J. 2019 May;33(5):6035-6044. doi: 10.1096/fj.201802118R. Epub 2019 Feb 6.

PMID:
30726111
16.

Unfolded protein response is an early, non-critical event during hepatic stellate cell activation.

Mannaerts I, Thoen LFR, Eysackers N, Cubero FJ, Batista Leite S, Coldham I, Colle I, Trautwein C, van Grunsven LA.

Cell Death Dis. 2019 Feb 4;10(2):98. doi: 10.1038/s41419-019-1327-5.

17.

CXCR6 Inhibits Hepatocarcinogenesis by Promoting Natural Killer T- and CD4+ T-Cell-Dependent Control of Senescence.

Mossanen JC, Kohlhepp M, Wehr A, Krenkel O, Liepelt A, Roeth AA, Möckel D, Heymann F, Lammers T, Gassler N, Hermann J, Jankowski J, Neumann UP, Luedde T, Trautwein C, Tacke F.

Gastroenterology. 2019 May;156(6):1877-1889.e4. doi: 10.1053/j.gastro.2019.01.247. Epub 2019 Jan 30.

PMID:
30710528
18.

The CCR2+ Macrophage Subset Promotes Pathogenic Angiogenesis for Tumor Vascularization in Fibrotic Livers.

Bartneck M, Schrammen PL, Möckel D, Govaere O, Liepelt A, Krenkel O, Ergen C, McCain MV, Eulberg D, Luedde T, Trautwein C, Kiessling F, Reeves H, Lammers T, Tacke F.

Cell Mol Gastroenterol Hepatol. 2019;7(2):371-390. doi: 10.1016/j.jcmgh.2018.10.007. Epub 2018 Oct 18.

19.

Polypropylene mesh implantation for hernia repair causes myeloid cell-driven persistent inflammation.

Heymann F, von Trotha KT, Preisinger C, Lynen-Jansen P, Roeth AA, Geiger M, Geisler LJ, Frank AK, Conze J, Luedde T, Trautwein C, Binnebösel M, Neumann UP, Tacke F.

JCI Insight. 2019 Jan 24;4(2). pii: 123862. doi: 10.1172/jci.insight.123862. [Epub ahead of print]

20.

Serum levels of miR-29, miR-122, miR-155 and miR-192 are elevated in patients with cholangiocarcinoma.

Loosen SH, Lurje G, Wiltberger G, Vucur M, Koch A, Kather JN, Paffenholz P, Tacke F, Ulmer FT, Trautwein C, Luedde T, Neumann UP, Roderburg C.

PLoS One. 2019 Jan 17;14(1):e0210944. doi: 10.1371/journal.pone.0210944. eCollection 2019.

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