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Organs to Cells and Cells to Organoids: The Evolution of in vitro Central Nervous System Modelling.

Pacitti D, Privolizzi R, Bax BE.

Front Cell Neurosci. 2019 Apr 9;13:129. doi: 10.3389/fncel.2019.00129. eCollection 2019. Review.


Safety and Efficacy of Erythrocyte Encapsulated Thymidine Phosphorylase in Mitochondrial Neurogastrointestinal Encephalomyopathy.

Levene M, Bain MD, Moran NF, Nirmalananthan N, Poulton J, Scarpelli M, Filosto M, Mandel H, MacKinnon AD, Fairbanks L, Pacitti D, Bax BE.

J Clin Med. 2019 Apr 5;8(4). pii: E457. doi: 10.3390/jcm8040457.


Mitochondrial Neurogastrointestinal Encephalomyopathy: Into the Fourth Decade, What We Have Learned So Far.

Pacitti D, Levene M, Garone C, Nirmalananthan N, Bax BE.

Front Genet. 2018 Dec 21;9:669. doi: 10.3389/fgene.2018.00669. eCollection 2018. Review.


Discovery profiling and bioinformatics analysis of serum microRNA in Mitochondrial NeuroGastroIntestinal Encephalomyopathy (MNGIE).

Levene M, Enguita FJ, Bax BE.

Nucleosides Nucleotides Nucleic Acids. 2018;37(11):618-629. doi: 10.1080/15257770.2018.1492138. Epub 2018 Dec 27.


Validation of an Immunoassay for Anti-thymidine Phosphorylase Antibodies in Patients with MNGIE Treated with Enzyme Replacement Therapy.

Levene M, Pacitti D, Gasson C, Hall J, Sellos-Moura M, Bax BE.

Mol Ther Methods Clin Dev. 2018 Aug 28;11:1-8. doi: 10.1016/j.omtm.2018.08.007. eCollection 2018 Dec 14.


Drug-loaded erythrocytes: on the road toward marketing approval.

Bourgeaux V, Lanao JM, Bax BE, Godfrin Y.

Drug Des Devel Ther. 2016 Feb 11;10:665-76. doi: 10.2147/DDDT.S96470. eCollection 2016. Review.


Clinical and biochemical improvements in a patient with MNGIE following enzyme replacement.

Bax BE, Bain MD, Scarpelli M, Filosto M, Tonin P, Moran N.

Neurology. 2013 Oct 1;81(14):1269-71. doi: 10.1212/WNL.0b013e3182a6cb4b. Epub 2013 Aug 21. No abstract available.


Differences in collagen ultrastructure of human first trimester decidua basalis and parietalis: implications for trophoblastic invasion of the placental bed.

Sinai Talaulikar V, Kronenberger K, Bax BE, Moss R, Manyonda I.

J Obstet Gynaecol Res. 2014 Jan;40(1):80-8. doi: 10.1111/jog.12127. Epub 2013 Aug 12.


Unexplained gastrointestinal symptoms: think mitochondrial disease.

Chapman TP, Hadley G, Fratter C, Cullen SN, Bax BE, Bain MD, Sapsford RA, Poulton J, Travis SP.

Dig Liver Dis. 2014 Jan;46(1):1-8. doi: 10.1016/j.dld.2013.04.008. Epub 2013 Jun 13.


Poor Outcome in a Mitochondrial Neurogastrointestinal Encephalomyopathy Patient with a Novel TYMP Mutation: The Need for Early Diagnosis.

Scarpelli M, Russignan A, Zombor M, Bereczki C, Zappini F, Buono R, Bax BE, Padovani A, Tonin P, Filosto M.

Case Rep Neurol. 2012 Sep;4(3):248-53. doi: 10.1159/000346260. Epub 2012 Dec 20.


Validation of a HPLC method for the measurement of erythrocyte encapsulated thymidine phosphorylase (EE-TP) activity.

Fairbanks LD, Levene M, Bax BE.

J Pharm Biomed Anal. 2013 Mar 25;76:8-12. doi: 10.1016/j.jpba.2012.12.006. Epub 2012 Dec 17.


The development and validation of an immunoassay for the measurement of anti-thymidine phosphorylase antibodies in mouse and dog sera.

Gasson C, Levene M, Bax BE.

J Pharm Biomed Anal. 2013 Jan;72:16-24. doi: 10.1016/j.jpba.2012.09.009. Epub 2012 Sep 23.


Preclinical toxicity evaluation of erythrocyte-encapsulated thymidine phosphorylase in BALB/c mice and beagle dogs: an enzyme-replacement therapy for mitochondrial neurogastrointestinal encephalomyopathy.

Levene M, Coleman DG, Kilpatrick HC, Fairbanks LD, Gangadharan B, Gasson C, Bax BE.

Toxicol Sci. 2013 Jan;131(1):311-24. doi: 10.1093/toxsci/kfs278. Epub 2012 Sep 12.


International seminar on the red blood cells as vehicles for drugs.

Godfrin Y, Horand F, Franco R, Dufour E, Kosenko E, Bax BE, Banz A, Skorokhod OA, Lanao JM, Vitvitsky V, Sinauridze E, Bourgeaux V, Gunter KC.

Expert Opin Biol Ther. 2012 Jan;12(1):127-33. doi: 10.1517/14712598.2012.631909. Epub 2011 Oct 25. No abstract available.


Seeking optimal relation between oxygen saturation and hemoglobin concentration in adults with cyanosis from congenital heart disease.

Broberg CS, Jayaweera AR, Diller GP, Prasad SK, Thein SL, Bax BE, Burman J, Gatzoulis MA.

Am J Cardiol. 2011 Feb 15;107(4):595-9. doi: 10.1016/j.amjcard.2010.10.019.


Mitochondrial neurogastrointestinal encephalopathy without elevated thymidine levels.

Moran NF, Baine M, Bax BE.

Arch Neurol. 2010 May;67(5):644; author reply 644-5. doi: 10.1001/archneurol.2010.73. No abstract available.


In vitro studies of amikacin-loaded human carrier erythrocytes.

Gutiérrez Millán C, Bax BE, Castañeda AZ, Marinero ML, Lanao JM.

Transl Res. 2008 Aug;152(2):59-66. doi: 10.1016/j.trsl.2008.05.008. Epub 2008 Jun 26.


Pulmonary arterial thrombosis in eisenmenger syndrome is associated with biventricular dysfunction and decreased pulmonary flow velocity.

Broberg CS, Ujita M, Prasad S, Li W, Rubens M, Bax BE, Davidson SJ, Bouzas B, Gibbs JS, Burman J, Gatzoulis MA.

J Am Coll Cardiol. 2007 Aug 14;50(7):634-42. Epub 2007 Jul 30.


A 9-yr evaluation of carrier erythrocyte encapsulated adenosine deaminase (ADA) therapy in a patient with adult-type ADA deficiency.

Bax BE, Bain MD, Fairbanks LD, Webster AD, Ind PW, Hershfield MS, Chalmers RA.

Eur J Haematol. 2007 Oct;79(4):338-48. Epub 2007 Aug 3.


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