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Items: 1 to 20 of 88


One century of ConA and 40 years of ConBr research: A structural review.

Cavada BS, Osterne VJS, Lossio CF, Pinto-Junior VR, Oliveira MV, Silva MTL, Leal RB, Nascimento KS.

Int J Biol Macromol. 2019 May 17. pii: S0141-8130(19)32136-1. doi: 10.1016/j.ijbiomac.2019.05.100. [Epub ahead of print] Review.


ConBr, The Lectin From Canavalia brasiliensis Mart. Seeds: Forty Years Of Research.

Cavada BS, Osterne VJS, Pinto-Junior VR, Nascimento KS.

Curr Protein Pept Sci. 2019 Jan 4. doi: 10.2174/1389203720666190104123210. [Epub ahead of print]


Lectin purified from Lonchocarpus campestris seeds inhibits inflammatory nociception.

de Freitas Pires A, Bezerra MM, Amorim RMF, do Nascimento FLF, Marinho MM, Moura RM, Silva MTL, Correia JLA, Cavada BS, Assreuy AMS, Nascimento KS.

Int J Biol Macromol. 2019 Mar 15;125:53-60. doi: 10.1016/j.ijbiomac.2018.11.233. Epub 2018 Nov 27.


Homology modeling, molecular docking, and dynamics of two α-methyl-D-mannoside-specific lectins from Arachis genus.

Nascimento KS, Araripe DA, Pinto-Junior VR, Osterne VJS, Martins FWV, Neco AHB, Farias GA, Cavada BS.

J Mol Model. 2018 Aug 25;24(9):251. doi: 10.1007/s00894-018-3800-y.


Structural analysis, molecular docking and molecular dynamics of an edematogenic lectin from Centrolobium microchaete seeds.

Neco AHB, Pinto-Junior VR, Araripe DA, Santiago MQ, Osterne VJS, Lossio CF, Nobre CAS, Oliveira MV, Silva MTL, Martins MGQ, Cajazeiras JB, Marques GFO, Costa DR, Nascimento KS, Assreuy AMS, Cavada BS.

Int J Biol Macromol. 2018 Oct 1;117:124-133. doi: 10.1016/j.ijbiomac.2018.05.166. Epub 2018 May 24.


Crystal structure of DlyL, a mannose-specific lectin from Dioclea lasiophylla Mart. Ex Benth seeds that display cytotoxic effects against C6 glioma cells.

Leal RB, Pinto-Junior VR, Osterne VJS, Wolin IAV, Nascimento APM, Neco AHB, Araripe DA, Welter PG, Neto CC, Correia JLA, Rocha CRC, Nascimento KS, Cavada BS.

Int J Biol Macromol. 2018 Jul 15;114:64-76. doi: 10.1016/j.ijbiomac.2018.03.080. Epub 2018 Mar 17. No abstract available.


Structural analysis of Dioclea lasiocarpa lectin: A C6 cells apoptosis-inducing protein.

Nascimento KS, Santiago MQ, Pinto-Junior VR, Osterne VJS, Martins FWV, Nascimento APM, Wolin IAV, Heinrich IA, Martins MGQ, Silva MTL, Lossio CF, Rocha CRC, Leal RB, Cavada BS.

Int J Biochem Cell Biol. 2017 Nov;92:79-89. doi: 10.1016/j.biocel.2017.09.014. Epub 2017 Sep 20.


Structural studies and nociceptive activity of a native lectin from Platypodium elegans seeds (nPELa).

Cavada BS, Araripe DA, Silva IB, Pinto-Junior VR, Osterne VJS, Neco AHB, Laranjeira EPP, Lossio CF, Correia JLA, Pires AF, Assreuy AMS, Nascimento KS.

Int J Biol Macromol. 2018 Feb;107(Pt A):236-246. doi: 10.1016/j.ijbiomac.2017.08.174. Epub 2017 Sep 1.


Canavalia bonariensis lectin: Molecular bases of glycoconjugates interaction and antiglioma potential.

Cavada BS, Silva MTL, Osterne VJS, Pinto-Junior VR, Nascimento APM, Wolin IAV, Heinrich IA, Nobre CAS, Moreira CG, Lossio CF, Rocha CRC, Martins JL, Nascimento KS, Leal RB.

Int J Biol Macromol. 2018 Jan;106:369-378. doi: 10.1016/j.ijbiomac.2017.08.023. Epub 2017 Aug 10.


Crystal structure of Pisum arvense seed lectin (PAL) and characterization of its interaction with carbohydrates by molecular docking and dynamics.

Pinto-Junior VR, Santiago MQ, Nobre CB, Osterne VJS, Leal RB, Cajazeiras JB, Lossio CF, Rocha BAM, Martins MGQ, Nobre CAS, Silva MTL, Nascimento KS, Cavada BS.

Arch Biochem Biophys. 2017 Sep 15;630:27-37. doi: 10.1016/ Epub 2017 Jul 25.


Partial characterization and immobilization in CNBr-activated Sepharose of a native lectin from Platypodium elegans seeds (PELa) and comparative study of edematogenic effect with the recombinant form.

Araripe DA, Pinto-Junior VR, Neco AHB, Santiago MQ, Osterne VJS, Pires AF, Lossio CF, Martins MGQ, Correia JLA, Benevides RG, Leal RB, Assreuy AMS, Nascimento KS, Cavada BS.

Int J Biol Macromol. 2017 Sep;102:323-330. doi: 10.1016/j.ijbiomac.2017.03.193. Epub 2017 Apr 2.


Molecular modeling, docking and dynamics simulations of the Dioclea lasiophylla Mart. Ex Benth seed lectin: An edematogenic and hypernociceptive protein.

Pinto-Junior VR, Osterne VJS, Santiago MQ, Lossio CF, Nagano CS, Rocha CRC, Nascimento JCF, Nascimento FLF, Silva IB, Oliveira AS, Correia JLA, Leal RB, Assreuy AMS, Cavada BS, Nascimento KS.

Biochimie. 2017 Apr;135:126-136. doi: 10.1016/j.biochi.2017.02.002. Epub 2017 Feb 11.


Structural studies of a vasorelaxant lectin from Dioclea reflexa Hook seeds: Crystal structure, molecular docking and dynamics.

Pinto-Junior VR, Osterne VJ, Santiago MQ, Correia JL, Pereira-Junior FN, Leal RB, Pereira MG, Chicas LS, Nagano CS, Rocha BA, Silva-Filho JC, Ferreira WP, Rocha CR, Nascimento KS, Assreuy AM, Cavada BS.

Int J Biol Macromol. 2017 May;98:12-23. doi: 10.1016/j.ijbiomac.2017.01.092. Epub 2017 Jan 24.


Structural characterization of a lectin from Canavalia virosa seeds with inflammatory and cytotoxic activities.

Osterne VJS, Silva-Filho JC, Santiago MQ, Pinto-Junior VR, Almeida AC, Barreto AAGC, Wolin IAV, Nascimento APM, Amorim RMF, Rocha BAM, Delatorre P, Nagano CS, Leal RB, Assreuy AMS, Nascimento KS, Cavada BS.

Int J Biol Macromol. 2017 Jan;94(Pt A):271-282. doi: 10.1016/j.ijbiomac.2016.10.020. Epub 2016 Oct 11.


Structure prediction and functional analysis of a non-permutated lectin from Dioclea grandiflora.

de Sousa BL, Nagano CS, Simões RD, Silva-Filho JC, Cunha RM, Cajazeiras JB, do Nascimento KS, Cavada BS.

Biochimie. 2016 Dec;131:54-67. doi: 10.1016/j.biochi.2016.09.010. Epub 2016 Sep 21.


Lectins from Parkia biglobosa and Parkia platycephala: A comparative study of structure and biological effects.

Bari AU, Santiago MQ, Osterne VJ, Pinto-Junior VR, Pereira LP, Silva-Filho JC, Debray H, Rocha BA, Delatorre P, Teixeira CS, Neto CC, Assreuy AM, Nascimento KS, Cavada BS.

Int J Biol Macromol. 2016 Nov;92:194-201. doi: 10.1016/j.ijbiomac.2016.07.032. Epub 2016 Jul 10.


Ultrasound processing to enhance drying of cashew apple bagasse puree: Influence on antioxidant properties and in vitro bioaccessibility of bioactive compounds.

Fonteles TV, Leite AK, Silva AR, Carneiro AP, Miguel Ede C, Cavada BS, Fernandes FA, Rodrigues S.

Ultrason Sonochem. 2016 Jul;31:237-49. doi: 10.1016/j.ultsonch.2016.01.003. Epub 2016 Jan 6.


Structural analysis of Centrolobium tomentosum seed lectin with inflammatory activity.

Almeida AC, Osterne VJ, Santiago MQ, Pinto-Junior VR, Silva-Filho JC, Lossio CF, Nascimento FL, Almeida RP, Teixeira CS, Leal RB, Delatorre P, Rocha BA, Assreuy AM, Nascimento KS, Cavada BS.

Arch Biochem Biophys. 2016 Apr 15;596:73-83. doi: 10.1016/ Epub 2016 Mar 3.


Purification of a thermostable antinociceptive lectin isolated from Andira anthelmia.

Nascimento KS, Nascimento FL, Silva MT, Nobre CB, Moreira CG, Brizeno LA, da Ponte EL, Assreuy AM, Cavada BS.

J Mol Recognit. 2016 Jun;29(6):248-52. doi: 10.1002/jmr.2523. Epub 2015 Dec 6.


A novel vasorelaxant lectin purified from seeds of Clathrotropis nitida: partial characterization and immobilization in chitosan beads.

Alves AC, Vasconcelos MA, Santiago MQ, Pinto-Junior VR, Silva Osterne VJ, Lossio CF, Bringel PH, Castro RR, Nagano CS, Delatorre P, Souza LA, Nascimento KS, Assreuy AM, Cavada BS.

Arch Biochem Biophys. 2015 Dec 15;588:33-40. doi: 10.1016/ Epub 2015 Nov 3.

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