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Items: 1 to 20 of 28


Zeptomole per milliliter detection and quantification of edema factor in plasma by LC-MS/MS yields insights into toxemia and the progression of inhalation anthrax.

Lins RC, Boyer AE, Kuklenyik Z, Woolfitt AR, Goldstein J, Hoffmaster AR, Gallegos-Candela M, Leysath CE, Chen Z, Brumlow JO, Quinn CP, Bagarozzi DA Jr, Leppla SH, Barr JR.

Anal Bioanal Chem. 2019 May;411(12):2493-2509. doi: 10.1007/s00216-019-01730-4. Epub 2019 Mar 26.


Accurate and selective quantification of anthrax protective antigen in plasma by immunocapture and isotope dilution mass spectrometry.

Solano MI, Woolfitt AR, Boyer AE, Lins RC, Isbell K, Gallegos-Candela M, Moura H, Pierce CL, Barr JR.

Analyst. 2019 Mar 25;144(7):2264-2274. doi: 10.1039/c8an02479k.


Validated MALDI-TOF-MS method for anthrax lethal factor provides early diagnosis and evaluation of therapeutics.

Gallegos-Candela M, Boyer AE, Woolfitt AR, Brumlow J, Lins RC, Quinn CP, Hoffmaster AR, Meister G, Barr JR.

Anal Biochem. 2018 Feb 15;543:97-107. doi: 10.1016/j.ab.2017.12.007. Epub 2017 Dec 7.


Analysis of Anthrax Immune Globulin Intravenous with Antimicrobial Treatment in Injection Drug Users, Scotland, 2009-2010.

Cui X, Nolen LD, Sun J, Booth M, Donaldson L, Quinn CP, Boyer AE, Hendricks K, Shadomy S, Bothma P, Judd O, McConnell P, Bower WA, Eichacker PQ.

Emerg Infect Dis. 2017 Jan;23(1):56-65. doi: 10.3201/eid2301.160608.


Anthrax Toxin-Expressing Bacillus cereus Isolated from an Anthrax-Like Eschar.

Marston CK, Ibrahim H, Lee P, Churchwell G, Gumke M, Stanek D, Gee JE, Boyer AE, Gallegos-Candela M, Barr JR, Li H, Boulay D, Cronin L, Quinn CP, Hoffmaster AR.

PLoS One. 2016 Jun 3;11(6):e0156987. doi: 10.1371/journal.pone.0156987. eCollection 2016.


Antitoxin Treatment of Inhalation Anthrax: A Systematic Review.

Huang E, Pillai SK, Bower WA, Hendricks KA, Guarnizo JT, Hoyle JD, Gorman SE, Boyer AE, Quinn CP, Meaney-Delman D.

Health Secur. 2015 Nov-Dec;13(6):365-77. doi: 10.1089/hs.2015.0032. Review.


Mass Spectrometric Detection of Bacterial Protein Toxins and Their Enzymatic Activity.

Kalb SR, Boyer AE, Barr JR.

Toxins (Basel). 2015 Aug 31;7(9):3497-511. doi: 10.3390/toxins7093497. Review.


High-sensitivity MALDI-TOF MS quantification of anthrax lethal toxin for diagnostics and evaluation of medical countermeasures.

Boyer AE, Gallegos-Candela M, Quinn CP, Woolfitt AR, Brumlow JO, Isbell K, Hoffmaster AR, Lins RC, Barr JR.

Anal Bioanal Chem. 2015 Apr;407(10):2847-58. doi: 10.1007/s00216-015-8509-5. Epub 2015 Feb 12.


Detection of anthrax protective antigen (PA) using europium labeled anti-PA monoclonal antibody and time-resolved fluorescence.

Stoddard RA, Quinn CP, Schiffer JM, Boyer AE, Goldstein J, Bagarozzi DA, Soroka SD, Dauphin LA, Hoffmaster AR.

J Immunol Methods. 2014 Jun;408:78-88. doi: 10.1016/j.jim.2014.05.008. Epub 2014 May 22.


Lethal factor and anti-protective antigen IgG levels associated with inhalation anthrax, Minnesota, USA.

Sprenkle MD, Griffith J, Marinelli W, Boyer AE, Quinn CP, Pesik NT, Hoffmaster A, Keenan J, Juni BA, Blaney DD.

Emerg Infect Dis. 2014 Feb;20(2):310-4. doi: 10.3201/eid2002.130245.


Circulating lethal toxin decreases the ability of neutrophils to respond to Bacillus anthracis.

Weiner ZP, Ernst SM, Boyer AE, Gallegos-Candela M, Barr JR, Glomski IJ.

Cell Microbiol. 2014 Apr;16(4):504-18. doi: 10.1111/cmi.12232. Epub 2013 Nov 6.


Debridement increases survival in a mouse model of subcutaneous anthrax.

Weiner ZP, Boyer AE, Gallegos-Candela M, Cardani AN, Barr JR, Glomski IJ.

PLoS One. 2012;7(2):e30201. doi: 10.1371/journal.pone.0030201. Epub 2012 Feb 29.


Lethal factor toxemia and anti-protective antigen antibody activity in naturally acquired cutaneous anthrax.

Boyer AE, Quinn CP, Beesley CA, Gallegos-Candela M, Marston CK, Cronin LX, Lins RC, Stoddard RA, Li H, Schiffer J, Hossain MJ, Chakraborty A, Rahman M, Luby SP, Shieh WJ, Zaki S, Barr JR, Hoffmaster AR.

J Infect Dis. 2011 Nov;204(9):1321-7. doi: 10.1093/infdis/jir543. Epub 2011 Sep 9.


Quantitative mass spectrometry for bacterial protein toxins--a sensitive, specific, high-throughput tool for detection and diagnosis.

Boyer AE, Gallegos-Candela M, Lins RC, Kuklenyik Z, Woolfitt A, Moura H, Kalb S, Quinn CP, Barr JR.

Molecules. 2011 Mar 14;16(3):2391-413. doi: 10.3390/molecules16032391. Review.


Antibody responses to a spore carbohydrate antigen as a marker of nonfatal inhalation anthrax in rhesus macaques.

Saile E, Boons GJ, Buskas T, Carlson RW, Kannenberg EL, Barr JR, Boyer AE, Gallegos-Candela M, Quinn CP.

Clin Vaccine Immunol. 2011 May;18(5):743-8. doi: 10.1128/CVI.00475-10. Epub 2011 Mar 9.


Comparison of MALDI-TOF-MS and HPLC-ESI-MS/MS for endopeptidase activity-based quantification of Anthrax lethal factor in serum.

Kuklenyik Z, Boyer AE, Lins R, Quinn CP, Gallegos-Candela M, Woolfitt A, Pirkle JL, Barr JR.

Anal Chem. 2011 Mar 1;83(5):1760-5. doi: 10.1021/ac1030144. Epub 2011 Feb 8.


Interferon-inducible CXC chemokines directly contribute to host defense against inhalational anthrax in a murine model of infection.

Crawford MA, Burdick MD, Glomski IJ, Boyer AE, Barr JR, Mehrad B, Strieter RM, Hughes MA.

PLoS Pathog. 2010 Nov 18;6(11):e1001199. doi: 10.1371/journal.ppat.1001199.


Anthrax: modern exposure science combats a deadly, ancient disease.

Barr JR, Boyer AE, Quinn CP.

J Expo Sci Environ Epidemiol. 2010 Nov;20(7):573-4. doi: 10.1038/jes.2010.49. No abstract available.


Integrated microfluidic enzyme reactor mass spectrometry platform for detection of anthrax lethal factor.

Aravamudhan S, Joseph PJ, Kuklenyik Z, Boyer AE, Barr JR.

Conf Proc IEEE Eng Med Biol Soc. 2009;2009:1071-4. doi: 10.1109/IEMBS.2009.5335064.


Kinetics of lethal factor and poly-D-glutamic acid antigenemia during inhalation anthrax in rhesus macaques.

Boyer AE, Quinn CP, Hoffmaster AR, Kozel TR, Saile E, Marston CK, Percival A, Plikaytis BD, Woolfitt AR, Gallegos M, Sabourin P, McWilliams LG, Pirkle JL, Barr JR.

Infect Immun. 2009 Aug;77(8):3432-41. doi: 10.1128/IAI.00346-09. Epub 2009 Jun 8.

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