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Items: 1 to 20 of 69


Endothelial cell senescence in aging-related vascular dysfunction.

Jia G, Aroor AR, Jia C, Sowers JR.

Biochim Biophys Acta Mol Basis Dis. 2019 Jul 1;1865(7):1802-1809. doi: 10.1016/j.bbadis.2018.08.008. Epub 2018 Aug 18. Review.


The combination of a neprilysin inhibitor (sacubitril) and angiotensin-II receptor blocker (valsartan) attenuates glomerular and tubular injury in the Zucker Obese rat.

Habibi J, Aroor AR, Das NA, Manrique-Acevedo CM, Johnson MS, Hayden MR, Nistala R, Wiedmeyer C, Chandrasekar B, DeMarco VG.

Cardiovasc Diabetol. 2019 Mar 25;18(1):40. doi: 10.1186/s12933-019-0847-8.


Empagliflozin Ameliorates Type 2 Diabetes-Induced Ultrastructural Remodeling of the Neurovascular Unit and Neuroglia in the Female db/db Mouse.

Hayden MR, Grant DG, Aroor AR, DeMarco VG.

Brain Sci. 2019 Mar 7;9(3). pii: E57. doi: 10.3390/brainsci9030057.


Diet-Induced Obesity Promotes Kidney Endothelial Stiffening and Fibrosis Dependent on the Endothelial Mineralocorticoid Receptor.

Aroor AR, Habibi J, Nistala R, Ramirez-Perez FI, Martinez-Lemus LA, Jaffe IZ, Sowers JR, Jia G, Whaley-Connell A.

Hypertension. 2019 Apr;73(4):849-858. doi: 10.1161/HYPERTENSIONAHA.118.12198.


Deficiency of IL12p40 (Interleukin 12 p40) Promotes Ang II (Angiotensin II)-Induced Abdominal Aortic Aneurysm.

Sharma N, Dev R, Belenchia AM, Aroor AR, Whaley-Connell A, Pulakat L, Hans CP.

Arterioscler Thromb Vasc Biol. 2019 Feb;39(2):212-223. doi: 10.1161/ATVBAHA.118.311969.


Glycemic control by the SGLT2 inhibitor empagliflozin decreases aortic stiffness, renal resistivity index and kidney injury.

Aroor AR, Das NA, Carpenter AJ, Habibi J, Jia G, Ramirez-Perez FI, Martinez-Lemus L, Manrique-Acevedo CM, Hayden MR, Duta C, Nistala R, Mayoux E, Padilla J, Chandrasekar B, DeMarco VG.

Cardiovasc Diabetol. 2018 Jul 30;17(1):108. doi: 10.1186/s12933-018-0750-8.


Role of Renin-Angiotensin-Aldosterone System Activation in Promoting Cardiovascular Fibrosis and Stiffness.

Jia G, Aroor AR, Hill MA, Sowers JR.

Hypertension. 2018 Sep;72(3):537-548. doi: 10.1161/HYPERTENSIONAHA.118.11065. Review. No abstract available.


Epithelial Sodium Channel in Aldosterone-Induced Endothelium Stiffness and Aortic Dysfunction.

Jia G, Habibi J, Aroor AR, Hill MA, Yang Y, Whaley-Connell A, Jaisser F, Sowers JR.

Hypertension. 2018 Sep;72(3):731-738. doi: 10.1161/HYPERTENSIONAHA.118.11339.


Potential Role of Antihypertensive Medications in Preventing Excessive Arterial Stiffening.

Jia G, Aroor AR, Martinez-Lemus LA, Sowers JR.

Curr Hypertens Rep. 2018 Jul 6;20(9):76. doi: 10.1007/s11906-018-0876-9. Review.


The role of dipeptidylpeptidase-4 inhibitors in management of cardiovascular disease in diabetes; focus on linagliptin.

Aroor AR, Manrique-Acevedo C, DeMarco VG.

Cardiovasc Diabetol. 2018 Apr 18;17(1):59. doi: 10.1186/s12933-018-0704-1. Review.


Cellular mechanisms underlying obesity-induced arterial stiffness.

Aroor AR, Jia G, Sowers JR.

Am J Physiol Regul Integr Comp Physiol. 2018 Mar 1;314(3):R387-R398. doi: 10.1152/ajpregu.00235.2016. Epub 2017 Nov 22. Review.


Dipeptidyl Peptidase-4 Inhibition With Saxagliptin Ameliorates Angiotensin II-Induced Cardiac Diastolic Dysfunction in Male Mice.

Brown SM, Smith CE, Meuth AI, Khan M, Aroor AR, Cleeton HM, Meininger GA, Sowers JR, DeMarco VG, Chandrasekar B, Nistala R, Bender SB.

Endocrinology. 2017 Oct 1;158(10):3592-3604. doi: 10.1210/en.2017-00416.


Enhanced endothelium epithelial sodium channel signaling prompts left ventricular diastolic dysfunction in obese female mice.

Jia G, Habibi J, Aroor AR, Hill MA, DeMarco VG, Lee LE, Ma L, Barron BJ, Whaley-Connell A, Sowers JR.

Metabolism. 2018 Jan;78:69-79. doi: 10.1016/j.metabol.2017.08.008. Epub 2017 Sep 8.


The role of mineralocorticoid receptor signaling in the cross-talk between adipose tissue and the vascular wall.

Jia G, Aroor AR, Sowers JR.

Cardiovasc Res. 2017 Jul 1;113(9):1055-1063. doi: 10.1093/cvr/cvx097. Review.


Uric acid promotes vascular stiffness, maladaptive inflammatory responses and proteinuria in western diet fed mice.

Aroor AR, Jia G, Habibi J, Sun Z, Ramirez-Perez FI, Brady B, Chen D, Martinez-Lemus LA, Manrique C, Nistala R, Whaley-Connell AT, Demarco VG, Meininger GA, Sowers JR.

Metabolism. 2017 Sep;74:32-40. doi: 10.1016/j.metabol.2017.06.006. Epub 2017 Jun 21.


Amiloride Improves Endothelial Function and Reduces Vascular Stiffness in Female Mice Fed a Western Diet.

Martinez-Lemus LA, Aroor AR, Ramirez-Perez FI, Jia G, Habibi J, DeMarco VG, Barron B, Whaley-Connell A, Nistala R, Sowers JR.

Front Physiol. 2017 Jun 30;8:456. doi: 10.3389/fphys.2017.00456. eCollection 2017.


Xanthine oxidase inhibition protects against Western diet-induced aortic stiffness and impaired vasorelaxation in female mice.

Lastra G, Manrique C, Jia G, Aroor AR, Hayden MR, Barron BJ, Niles B, Padilla J, Sowers JR.

Am J Physiol Regul Integr Comp Physiol. 2017 Aug 1;313(2):R67-R77. doi: 10.1152/ajpregu.00483.2016. Epub 2017 May 24.


Dipeptidyl peptidase-4 (DPP-4) inhibition with linagliptin reduces western diet-induced myocardial TRAF3IP2 expression, inflammation and fibrosis in female mice.

Aroor AR, Habibi J, Kandikattu HK, Garro-Kacher M, Barron B, Chen D, Hayden MR, Whaley-Connell A, Bender SB, Klein T, Padilla J, Sowers JR, Chandrasekar B, DeMarco VG.

Cardiovasc Diabetol. 2017 May 5;16(1):61. doi: 10.1186/s12933-017-0544-4.


Absence of Endothelial ERĪ± Results in Arterial Remodeling and Decreased Stiffness in Western Diet-Fed Male Mice.

Manrique-Acevedo C, Ramirez-Perez FI, Padilla J, Vieira-Potter VJ, Aroor AR, Barron BJ, Chen D, Haertling D, Declue C, Sowers JR, Martinez-Lemus LA.

Endocrinology. 2017 Jun 1;158(6):1875-1885. doi: 10.1210/en.2016-1831.


Sodium glucose transporter 2 (SGLT2) inhibition with empagliflozin improves cardiac diastolic function in a female rodent model of diabetes.

Habibi J, Aroor AR, Sowers JR, Jia G, Hayden MR, Garro M, Barron B, Mayoux E, Rector RS, Whaley-Connell A, DeMarco VG.

Cardiovasc Diabetol. 2017 Jan 13;16(1):9. doi: 10.1186/s12933-016-0489-z.

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