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Items: 1 to 20 of 54

1.

Ovarian Tumor Microenvironment Signaling: Convergence on the Rac1 GTPase.

Hudson LG, Gillette JM, Kang H, Rivera MR, Wandinger-Ness A.

Cancers (Basel). 2018 Sep 27;10(10). pii: E358. doi: 10.3390/cancers10100358. Review.

2.

Small-Volume Flow Cytometry-Based Multiplex Analysis of the Activity of Small GTPases.

Simons P, Bondu V, Wandinger-Ness A, Buranda T.

Methods Mol Biol. 2018;1821:177-195. doi: 10.1007/978-1-4939-8612-5_13.

3.

Activation of Rho Family GTPases by Small Molecules.

Palsuledesai CC, Surviladze Z, Waller A, Miscioscia TF, Guo Y, Wu Y, Strouse J, Romero E, Salas VM, Curpan R, Young S, Carter M, Foutz T, Galochkina Z, Ames H, Haynes MK, Edwards BS, Nicolotti O, Luo L, Ursu O, Bologa CG, Oprea TI, Wandinger-Ness A, Sklar LA.

ACS Chem Biol. 2018 Jun 15;13(6):1514-1524. doi: 10.1021/acschembio.8b00038. Epub 2018 May 24.

4.

The R-Enantiomer of Ketorolac Delays Mammary Tumor Development in Mouse Mammary Tumor Virus-Polyoma Middle T Antigen (MMTV-PyMT) Mice.

Peretti AS, Dominguez D, Grimes MM, Hathaway HJ, Prossnitz ER, Rivera MR, Wandinger-Ness A, Kusewitt DF, Hudson LG.

Am J Pathol. 2018 Feb;188(2):515-524. doi: 10.1016/j.ajpath.2017.10.018. Epub 2017 Nov 21.

5.

Transcriptome analysis reveals manifold mechanisms of cyst development in ADPKD.

de Almeida RM, Clendenon SG, Richards WG, Boedigheimer M, Damore M, Rossetti S, Harris PC, Herbert BS, Xu WM, Wandinger-Ness A, Ward HH, Glazier JA, Bacallao RL.

Hum Genomics. 2016 Nov 21;10(1):37.

6.

Constrained inference of protein interaction networks for invadopodium formation in cancer.

Wang H, Leung M, Wandinger-Ness A, Hudson LG, Song M.

IET Syst Biol. 2016 Apr;10(2):76-85. doi: 10.1049/iet-syb.2015.0009.

7.

Novel Activities of Select NSAID R-Enantiomers against Rac1 and Cdc42 GTPases.

Oprea TI, Sklar LA, Agola JO, Guo Y, Silberberg M, Roxby J, Vestling A, Romero E, Surviladze Z, Murray-Krezan C, Waller A, Ursu O, Hudson LG, Wandinger-Ness A.

PLoS One. 2015 Nov 11;10(11):e0142182. doi: 10.1371/journal.pone.0142182. eCollection 2015.

8.

Epithelial Cell Repopulation and Preparation of Rodent Extracellular Matrix Scaffolds for Renal Tissue Development.

Uzarski JS, Su J, Xie Y, Zhang ZJ, Ward HH, Wandinger-Ness A, Miller WM, Wertheim JA.

J Vis Exp. 2015 Aug 10;(102):e53271. doi: 10.3791/53271.

9.

A Pan-GTPase Inhibitor as a Molecular Probe.

Hong L, Guo Y, BasuRay S, Agola JO, Romero E, Simpson DS, Schroeder CE, Simons P, Waller A, Garcia M, Carter M, Ursu O, Gouveia K, Golden JE, Aubé J, Wandinger-Ness A, Sklar LA.

PLoS One. 2015 Aug 6;10(8):e0134317. doi: 10.1371/journal.pone.0134317. eCollection 2015.

10.

R-Ketorolac Targets Cdc42 and Rac1 and Alters Ovarian Cancer Cell Behaviors Critical for Invasion and Metastasis.

Guo Y, Kenney SR, Muller CY, Adams S, Rutledge T, Romero E, Murray-Krezan C, Prekeris R, Sklar LA, Hudson LG, Wandinger-Ness A.

Mol Cancer Ther. 2015 Oct;14(10):2215-27. doi: 10.1158/1535-7163.MCT-15-0419. Epub 2015 Jul 23.

11.

A Novel Pharmacologic Activity of Ketorolac for Therapeutic Benefit in Ovarian Cancer Patients.

Guo Y, Kenney SR, Cook L, Adams SF, Rutledge T, Romero E, Oprea TI, Sklar LA, Bedrick E, Wiggins CL, Kang H, Lomo L, Muller CY, Wandinger-Ness A, Hudson LG.

Clin Cancer Res. 2015 Nov 15;21(22):5064-72. doi: 10.1158/1078-0432.CCR-15-0461. Epub 2015 Jun 12.

12.

Dual-Purpose Bioreactors to Monitor Noninvasive Physical and Biochemical Markers of Kidney and Liver Scaffold Recellularization.

Uzarski JS, Bijonowski BM, Wang B, Ward HH, Wandinger-Ness A, Miller WM, Wertheim JA.

Tissue Eng Part C Methods. 2015 Oct;21(10):1032-43. doi: 10.1089/ten.TEC.2014.0665. Epub 2015 Jun 26.

13.

Quantitative bead-based flow cytometry for assaying Rab7 GTPase interaction with the Rab-interacting lysosomal protein (RILP) effector protein.

Agola JO, Sivalingam D, Cimino DF, Simons PC, Buranda T, Sklar LA, Wandinger-Ness A.

Methods Mol Biol. 2015;1298:331-54. doi: 10.1007/978-1-4939-2569-8_28.

14.

Rab proteins and the compartmentalization of the endosomal system.

Wandinger-Ness A, Zerial M.

Cold Spring Harb Perspect Biol. 2014 Oct 23;6(11):a022616. doi: 10.1101/cshperspect.a022616. Review.

15.

OFD1 and flotillins are integral components of a ciliary signaling protein complex organized by polycystins in renal epithelia and odontoblasts.

Jerman S, Ward HH, Lee R, Lopes CA, Fry AM, MacDougall M, Wandinger-Ness A.

PLoS One. 2014 Sep 2;9(9):e106330. doi: 10.1371/journal.pone.0106330. eCollection 2014.

16.

Meeting report - Arf and Rab family G proteins.

Casanova JE, Hsu VW, Jackson CL, Kahn RA, Roy CR, Stow JL, Wandinger-Ness A, Sztul E.

J Cell Sci. 2013 Dec 1;126(Pt 23):5313-6. doi: 10.1242/jcs.143610.

17.

Rapid parallel flow cytometry assays of active GTPases using effector beads.

Buranda T, BasuRay S, Swanson S, Agola J, Bondu V, Wandinger-Ness A.

Anal Biochem. 2013 Nov 15;442(2):149-57. doi: 10.1016/j.ab.2013.07.039. Epub 2013 Aug 6.

18.

A small molecule pan-inhibitor of Ras-superfamily GTPases with high efficacy towards Rab7.

Hong L, Simons P, Waller A, Strouse J, Surviladze Z, Ursu O, Bologa C, Gouveia K, Agola JO, BasuRay S, Wandinger-Ness A, Sklar L, Simpson DS, Schroeder CE, Golden JE, Aubé J.

Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010-.
2011 Dec 16 [updated 2013 Mar 7].

19.

A telomerase immortalized human proximal tubule cell line with a truncation mutation (Q4004X) in polycystin-1.

Herbert BS, Grimes BR, Xu WM, Werner M, Ward C, Rossetti S, Harris P, Bello-Reuss E, Ward HH, Miller C, Gattone VH 2nd, Phillips CL, Wandinger-Ness A, Bacallao RL.

PLoS One. 2013;8(1):e55191. doi: 10.1371/journal.pone.0055191. Epub 2013 Jan 28.

20.

Characterization of a Cdc42 protein inhibitor and its use as a molecular probe.

Hong L, Kenney SR, Phillips GK, Simpson D, Schroeder CE, Nöth J, Romero E, Swanson S, Waller A, Strouse JJ, Carter M, Chigaev A, Ursu O, Oprea T, Hjelle B, Golden JE, Aubé J, Hudson LG, Buranda T, Sklar LA, Wandinger-Ness A.

J Biol Chem. 2013 Mar 22;288(12):8531-43. doi: 10.1074/jbc.M112.435941. Epub 2013 Feb 4. Erratum in: J Biol Chem. 2014 Mar 7;289(10):6837.

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