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Items: 12


The prebiotic inulin modulates gut microbiota but does not ameliorate atherosclerosis in hypercholesterolemic APOE*3-Leiden.CETP mice.

Hoving LR, Katiraei S, Pronk A, Heijink M, Vonk KKD, Amghar-El Bouazzaoui F, Vermeulen R, Drinkwaard L, Giera M, van Harmelen V, Willems van Dijk K.

Sci Rep. 2018 Nov 8;8(1):16515. doi: 10.1038/s41598-018-34970-y.


Dietary yeast-derived mannan oligosaccharides have immune-modulatory properties but do not improve high fat diet-induced obesity and glucose intolerance.

Hoving LR, van der Zande HJP, Pronk A, Guigas B, Willems van Dijk K, van Harmelen V.

PLoS One. 2018 May 3;13(5):e0196165. doi: 10.1371/journal.pone.0196165. eCollection 2018.


Dietary Mannan Oligosaccharides Modulate Gut Microbiota, Increase Fecal Bile Acid Excretion, and Decrease Plasma Cholesterol and Atherosclerosis Development.

Hoving LR, Katiraei S, Heijink M, Pronk A, van der Wee-Pals L, Streefland T, Giera M, Willems van Dijk K, van Harmelen V.

Mol Nutr Food Res. 2018 May;62(10):e1700942. doi: 10.1002/mnfr.201700942.


The Prebiotic Inulin Aggravates Accelerated Atherosclerosis in Hypercholesterolemic APOE*3-Leiden Mice.

Hoving LR, de Vries MR, de Jong RCM, Katiraei S, Pronk A, Quax PHA, van Harmelen V, Willems van Dijk K.

Nutrients. 2018 Feb 3;10(2). pii: E172. doi: 10.3390/nu10020172.


The limited storage capacity of gonadal adipose tissue directs the development of metabolic disorders in male C57Bl/6J mice.

van Beek L, van Klinken JB, Pronk AC, van Dam AD, Dirven E, Rensen PC, Koning F, Willems van Dijk K, van Harmelen V.

Diabetologia. 2015 Jul;58(7):1601-9. doi: 10.1007/s00125-015-3594-8. Epub 2015 May 12.


Preclinical studies on intestinal administration of antisense oligonucleotides as a model for oral delivery for treatment of duchenne muscular dystrophy.

van Putten M, Young C, van den Berg S, Pronk A, Hulsker M, Karnaoukh TG, Vermue R, van Dijk KW, de Kimpe S, Aartsma-Rus A.

Mol Ther Nucleic Acids. 2014 Nov 18;3:e211. doi: 10.1038/mtna.2014.62.


Human TP53 polymorphism (rs1042522) modelled in mouse does not affect glucose metabolism and body composition.

Reiling E, Speksnijder EN, Pronk AC, van den Berg SA, Neggers SJ, Rietbroek I, van Steeg H, Dollé ME.

Sci Rep. 2014 Feb 13;4:4091. doi: 10.1038/srep04091.


Long-term niacin treatment induces insulin resistance and adrenergic responsiveness in adipocytes by adaptive downregulation of phosphodiesterase 3B.

Heemskerk MM, van den Berg SA, Pronk AC, van Klinken JB, Boon MR, Havekes LM, Rensen PC, van Dijk KW, van Harmelen V.

Am J Physiol Endocrinol Metab. 2014 Apr 1;306(7):E808-13. doi: 10.1152/ajpendo.00641.2013. Epub 2014 Jan 28.


Apolipoprotein A5 deficiency aggravates high-fat diet-induced obesity due to impaired central regulation of food intake.

van den Berg SA, Heemskerk MM, Geerling JJ, van Klinken JB, Schaap FG, Bijland S, Berbée JF, van Harmelen VJ, Pronk AC, Schreurs M, Havekes LM, Rensen PC, van Dijk KW.

FASEB J. 2013 Aug;27(8):3354-62. doi: 10.1096/fj.12-225367. Epub 2013 May 6.


Detrimental effects of constant light exposure and high-fat diet on circadian energy metabolism and insulin sensitivity.

Coomans CP, van den Berg SA, Houben T, van Klinken JB, van den Berg R, Pronk AC, Havekes LM, Romijn JA, van Dijk KW, Biermasz NR, Meijer JH.

FASEB J. 2013 Apr;27(4):1721-32. doi: 10.1096/fj.12-210898. Epub 2013 Jan 9.


The suprachiasmatic nucleus controls circadian energy metabolism and hepatic insulin sensitivity.

Coomans CP, van den Berg SA, Lucassen EA, Houben T, Pronk AC, van der Spek RD, Kalsbeek A, Biermasz NR, Willems van Dijk K, Romijn JA, Meijer JH.

Diabetes. 2013 Apr;62(4):1102-8. doi: 10.2337/db12-0507. Epub 2012 Dec 28.


Inhibition of type 2A secretory phospholipase A2 reduces death of cardiomyocytes in acute myocardial infarction.

van Dijk A, Krijnen PA, Vermond RA, Pronk A, Spreeuwenberg M, Visser FC, Berney R, Paulus WJ, Hack CE, van Milligen FJ, Niessen HW.

Apoptosis. 2009 Jun;14(6):753-63. doi: 10.1007/s10495-009-0350-x.


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