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Items: 1 to 20 of 30


Curcumin combined with metformin decreases glycemia and dyslipidemia, and increases paraoxonase activity in diabetic rats.

Roxo DF, Arcaro CA, Gutierres VO, Costa MC, Oliveira JO, Lima TFO, Assis RP, Brunetti IL, Baviera AM.

Diabetol Metab Syndr. 2019 Apr 30;11:33. doi: 10.1186/s13098-019-0431-0. eCollection 2019.


N, N', N″-trisubstituted guanidines: Synthesis, characterization and evaluation of their leishmanicidal activity.

do Espírito Santo RD, Velásquez ÁMA, Passianoto LVG, Sepulveda AAL, da Costa Clementino L, Assis RP, Baviera AM, Kalaba P, Dos Santos FN, Éberlin MN, da Silva GVJ, Zehl M, Lubec G, Graminha MAS, González ERP.

Eur J Med Chem. 2019 Jun 1;171:116-128. doi: 10.1016/j.ejmech.2019.03.032. Epub 2019 Mar 21.


Curcumin improves the effect of a reduced insulin dose on glycemic control and oxidative stress in streptozotocin-diabetic rats.

Gutierres VO, Assis RP, Arcaro CA, Oliveira JO, Lima TFO, Beretta ALRZ, Costa PI, Baviera AM, Brunetti IL.

Phytother Res. 2019 Apr;33(4):976-988. doi: 10.1002/ptr.6291. Epub 2019 Jan 18.


New compounds of Siolmatra brasiliensis and inhibition of in vitro protein glycation damage.

Dos Santos CHC, Talpo TC, Motta BP, Kaga AK, Baviera AM, Castro RN, da Silva VC, de Sousa-Junior PT, Wessjohann L, de Carvalho MG.

Fitoterapia. 2019 Mar;133:109-119. doi: 10.1016/j.fitote.2018.12.023. Epub 2018 Dec 31.


In vitro inhibition of protein glycation and advanced glycation end products formation by hydroethanolic extract and two fractions of Simaba trichilioides roots.

Motta BP, Kaga AK, Oliveira JO, Inacio MD, da Silva CF, de Sousa Junior PT, Brunetti IL, Baviera AM.

Nat Prod Res. 2018 Dec 22:1-5. doi: 10.1080/14786419.2018.1537276. [Epub ahead of print]


Emodin, Physcion, and Crude Extract of Rhamnus sphaerosperma var. pubescens Induce Mixed Cell Death, Increase in Oxidative Stress, DNA Damage, and Inhibition of AKT in Cervical and Oral Squamous Carcinoma Cell Lines.

Moreira TF, Sorbo JM, Souza FO, Fernandes BC, Ocampos FMM, de Oliveira DMS, Arcaro CA, Assis RP, Barison A, Miguel OG, Baviera AM, Soares CP, Brunetti IL.

Oxid Med Cell Longev. 2018 Jul 3;2018:2390234. doi: 10.1155/2018/2390234. eCollection 2018.


Repeated Exposition to Mercury (II) Chloride Enhances Susceptibility to S. schenckii sensu stricto Infection in Mice.

Batista-Duharte A, Téllez-Martínez D, Aparecida Jellmayer J, Leandro Portuondo Fuentes D, Campos Polesi M, Martins Baviera A, Zeppone Carlos I.

J Fungi (Basel). 2018 May 25;4(2). pii: E64. doi: 10.3390/jof4020064.


The role of organic cation transporter 2 inhibitor cimetidine, experimental diabetes mellitus and metformin on gabapentin pharmacokinetics in rats.

Benzi JRL, Yamamoto PA, Stevens JH, Baviera AM, de Moraes NV.

Life Sci. 2018 May 1;200:63-68. doi: 10.1016/j.lfs.2018.03.012. Epub 2018 Mar 15.


Insulin treatment reverses the increase in atrogin-1 expression in atrophied skeletal muscles of diabetic rats with acute joint inflammation.

Pinheiro-Dardis CM, Gutierres VO, Assis RP, Peviani SM, Delfino GB, Durigan JLQ, Salvini TF, Baviera AM, Brunetti IL.

Ther Clin Risk Manag. 2018 Feb 14;14:275-286. doi: 10.2147/TCRM.S142948. eCollection 2018.


Involvement of cAMP/EPAC/Akt signaling in the antiproteolytic effects of pentoxifylline on skeletal muscles of diabetic rats.

Arcaro CA, Assis RP, Zanon NM, Paula-Gomes S, Navegantes LCC, Kettelhut IC, Brunetti IL, Baviera AM.

J Appl Physiol (1985). 2018 Mar 1;124(3):704-716. doi: 10.1152/japplphysiol.00499.2017. Epub 2017 Dec 14.


Efficacy of a Binuclear Cyclopalladated Compound Therapy for Cutaneous Leishmaniasis in the Murine Model of Infection with Leishmania amazonensis and Its Inhibitory Effect on Topoisomerase 1B.

Velásquez AMA, Ribeiro WC, Venn V, Castelli S, Camargo MS, de Assis RP, de Souza RA, Ribeiro AR, Passalacqua TG, da Rosa JA, Baviera AM, Mauro AE, Desideri A, Almeida-Amaral EE, Graminha MAS.

Antimicrob Agents Chemother. 2017 Jul 25;61(8). pii: e00688-17. doi: 10.1128/AAC.00688-17. Print 2017 Aug.


Combined Effects of Curcumin and Lycopene or Bixin in Yoghurt on Inhibition of LDL Oxidation and Increases in HDL and Paraoxonase Levels in Streptozotocin-Diabetic Rats.

Assis RP, Arcaro CA, Gutierres VO, Oliveira JO, Costa PI, Baviera AM, Brunetti IL.

Int J Mol Sci. 2017 Mar 23;18(4). pii: E332. doi: 10.3390/ijms18040332.


Photodynamic therapy combined to cisplatin potentiates cell death responses of cervical cancer cells.

de Freitas LM, Serafim RB, de Sousa JF, Moreira TF, Dos Santos CT, Baviera AM, Valente V, Soares CP, Fontana CR.

BMC Cancer. 2017 Feb 10;17(1):123. doi: 10.1186/s12885-017-3075-1.


Higher insulin sensitivity in EDL muscle of rats fed a low-protein, high-carbohydrate diet inhibits the caspase-3 and ubiquitin-proteasome proteolytic systems but does not increase protein synthesis.

Dos Santos MP, Batistela E, Pereira MP, Paula-Gomes S, Zanon NM, Kettelhut Ido C, Karatzaferi C, Andrade CM, de França SA, Baviera AM, Kawashita NH.

J Nutr Biochem. 2016 Aug;34:89-98. doi: 10.1016/j.jnutbio.2016.04.008. Epub 2016 May 6.


Combretum lanceolatum flowers ethanol extract inhibits hepatic gluconeogenesis: an in vivo mechanism study.

Siqueira JT, Batistela E, Pereira MP, da Silva VC, de Sousa Junior PT, Andrade CM, Kawashita NH, Bertolini GL, Baviera AM.

Pharm Biol. 2016 Sep;54(9):1671-9. doi: 10.3109/13880209.2015.1120321. Epub 2016 Feb 10.


A new dammarane saponin and other triterpenoids from Siolmatra brasiliensis and evaluation of the antidiabetic activity of its extract.

Dos Santos CH, Borges IP, da Silva VC, de Sousa PT Jr, Kawashita NH, Baviera AM, Carvalho MG.

Pharm Biol. 2016 Sep;54(9):1539-47. doi: 10.3109/13880209.2015.1107108. Epub 2016 Jan 25.


Acute and subchronic antihyperglycemic activities of Bowdichia virgilioides roots in non-diabetic and diabetic rats.

Silva AC, Dos Santos MP, de França SA, da Silva VC, da Silva LE, de Figueiredo US, Dall'Oglio EL, Júnior PT, Lopes CF, Baviera AM, Kawashita NH.

J Intercult Ethnopharmacol. 2015 Jan-Mar;4(1):57-63. doi: 10.5455/jice.20141028022407. Epub 2014 Nov 28.


Curcumin Pharmacokinetic and Pharmacodynamic Evidences in Streptozotocin-Diabetic Rats Support the Antidiabetic Activity to Be via Metabolite(s).

Gutierres VO, Campos ML, Arcaro CA, Assis RP, Baldan-Cimatti HM, Peccinini RG, Paula-Gomes S, Kettelhut IC, Baviera AM, Brunetti IL.

Evid Based Complement Alternat Med. 2015;2015:678218. doi: 10.1155/2015/678218. Epub 2015 May 3.


Piperine, a natural bioenhancer, nullifies the antidiabetic and antioxidant activities of curcumin in streptozotocin-diabetic rats.

Arcaro CA, Gutierres VO, Assis RP, Moreira TF, Costa PI, Baviera AM, Brunetti IL.

PLoS One. 2014 Dec 3;9(12):e113993. doi: 10.1371/journal.pone.0113993. eCollection 2014.


Effects of the acute exposition to glyphosate-based herbicide on oxidative stress parameters and antioxidant responses in a hybrid Amazon fish surubim (Pseudoplatystoma sp).

Sinhorin VD, Sinhorin AP, Teixeira JM, Miléski KM, Hansen PC, Moreira PS, Kawashita NH, Baviera AM, Loro VL.

Ecotoxicol Environ Saf. 2014 Aug;106:181-7. doi: 10.1016/j.ecoenv.2014.04.040. Epub 2014 May 20.


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