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Items: 10


MSC-derived sEVs enhance patency and inhibit calcification of synthetic vascular grafts by immunomodulation in a rat model of hyperlipidemia.

Wei Y, Wu Y, Zhao R, Zhang K, Midgley AC, Kong D, Li Z, Zhao Q.

Biomaterials. 2019 Jun;204:13-24. doi: 10.1016/j.biomaterials.2019.01.049. Epub 2019 Mar 5.


Cobalt-mediated multi-functional dressings promote bacteria-infected wound healing.

Shi Q, Luo X, Huang Z, Midgley AC, Wang B, Liu R, Zhi D, Wei T, Zhou X, Qiao M, Zhang J, Kong D, Wang K.

Acta Biomater. 2019 Mar 1;86:465-479. doi: 10.1016/j.actbio.2018.12.048. Epub 2018 Dec 30.


Construction of a bilayered vascular graft with smooth internal surface for improved hemocompatibility and endothelial cell monolayer formation.

Dong X, Yuan X, Wang L, Liu J, Midgley AC, Wang Z, Wang K, Liu J, Zhu M, Kong D.

Biomaterials. 2018 Oct;181:1-14. doi: 10.1016/j.biomaterials.2018.07.027. Epub 2018 Jul 20.


Nuclear hyaluronidase 2 drives alternative splicing of CD44 pre-mRNA to determine profibrotic or antifibrotic cell phenotype.

Midgley AC, Oltean S, Hascall V, Woods EL, Steadman R, Phillips AO, Meran S.

Sci Signal. 2017 Nov 21;10(506). pii: eaao1822. doi: 10.1126/scisignal.aao1822.


Hepatocyte Growth Factor Mediates Enhanced Wound Healing Responses and Resistance to Transforming Growth Factor-β₁-Driven Myofibroblast Differentiation in Oral Mucosal Fibroblasts.

Dally J, Khan JS, Voisey A, Charalambous C, John HL, Woods EL, Steadman R, Moseley R, Midgley AC.

Int J Mol Sci. 2017 Aug 24;18(9). pii: E1843. doi: 10.3390/ijms18091843.


17β-estradiol ameliorates age-associated loss of fibroblast function by attenuating IFN-γ/STAT1-dependent miR-7 upregulation.

Midgley AC, Morris G, Phillips AO, Steadman R.

Aging Cell. 2016 Jun;15(3):531-41. doi: 10.1111/acel.12462. Epub 2016 Mar 2.


Hyaluronan regulates bone morphogenetic protein-7-dependent prevention and reversal of myofibroblast phenotype.

Midgley AC, Duggal L, Jenkins R, Hascall V, Steadman R, Phillips AO, Meran S.

J Biol Chem. 2015 May 1;290(18):11218-34. doi: 10.1074/jbc.M114.625939. Epub 2015 Feb 25.


MicroRNA-7 inhibition rescues age-associated loss of epidermal growth factor receptor and hyaluronan-dependent differentiation in fibroblasts.

Midgley AC, Bowen T, Phillips AO, Steadman R.

Aging Cell. 2014 Apr;13(2):235-44. doi: 10.1111/acel.12167. Epub 2013 Nov 12.


Transforming growth factor-β1 (TGF-β1)-stimulated fibroblast to myofibroblast differentiation is mediated by hyaluronan (HA)-facilitated epidermal growth factor receptor (EGFR) and CD44 co-localization in lipid rafts.

Midgley AC, Rogers M, Hallett MB, Clayton A, Bowen T, Phillips AO, Steadman R.

J Biol Chem. 2013 May 24;288(21):14824-38. doi: 10.1074/jbc.M113.451336. Epub 2013 Apr 15.

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