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Items: 1 to 20 of 91

1.

The impact of inosine triphosphatase variants on hemoglobin level and sustained virologic response of chronic hepatitis C in Korean.

Kim JS, Ahn SM, Jung YK, Kwon OS, Kim YS, Choi DJ, Kim JH.

J Korean Med Sci. 2013 Aug;28(8):1213-9. doi: 10.3346/jkms.2013.28.8.1213. Epub 2013 Jul 31.

2.

Analysis of human ITPase nucleobase specificity by site-directed mutagenesis.

Gall AD, Gall A, Moore AC, Aune MK, Heid S, Mori A, Burgis NE.

Biochimie. 2013 Sep;95(9):1711-21. doi: 10.1016/j.biochi.2013.05.016. Epub 2013 Jun 14.

PMID:
23770441
3.

Pre-treatment role of inosine triphosphate pyrophosphatase polymorphism for predicting anemia in Egyptian hepatitis C virus patients.

Ahmed WH, Furusyo N, Zaky S, Eldin AS, Aboalam H, Ogawa E, Murata M, Hayashi J.

World J Gastroenterol. 2013 Mar 7;19(9):1387-95. doi: 10.3748/wjg.v19.i9.1387.

4.

The human ITPA polymorphic variant P32T is destabilized by the unpacking of the hydrophobic core.

Simone PD, Struble LR, Kellezi A, Brown CA, Grabow CE, Khutsishvili I, Marky LA, Pavlov YI, Borgstahl GE.

J Struct Biol. 2013 Jun;182(3):197-208. doi: 10.1016/j.jsb.2013.03.007. Epub 2013 Mar 23.

5.

Several factors including ITPA polymorphism influence ribavirin-induced anemia in chronic hepatitis C.

Tsubota A, Shimada N, Abe H, Yoshizawa K, Agata R, Yumoto Y, Ika M, Namiki Y, Nagatsuma K, Matsudaira H, Fujise K, Tada N, Aizawa Y.

World J Gastroenterol. 2012 Nov 7;18(41):5879-88. doi: 10.3748/wjg.v18.i41.5879.

6.

ITPA gene polymorphisms significantly affect hemoglobin decline and treatment outcomes in patients coinfected with HIV and HCV.

Osinusi A, Naggie S, Poonia S, Trippler M, Hu Z, Funk E, Schlaak J, Fishbein D, Masur H, Polis M, Kottilil S.

J Med Virol. 2012 Jul;84(7):1106-14. doi: 10.1002/jmv.23302.

7.

Genetic variants at the ITPA locus protect against ribavirin-induced hemolytic anemia and dose reduction in an HCV G2/G3 cohort.

Eskesen AN, Melum E, Moghaddam A, Bjøro K, Verbaan H, Ring-Larsen H, Dalgard O.

Eur J Gastroenterol Hepatol. 2012 Aug;24(8):890-6. doi: 10.1097/MEG.0b013e3283546efd.

PMID:
22584257
8.

Increase in platelet count based on inosine triphosphatase genotype during interferon beta plus ribavirin combination therapy.

Nomura H, Miyagi Y, Tanimoto H, Yamashita N, Ito K, Masaki N, Mizokami M.

J Gastroenterol Hepatol. 2012 Sep;27(9):1461-6. doi: 10.1111/j.1440-1746.2012.07171.x.

PMID:
22554247
9.

Anemia and thrombocytosis induced by ribavirin monotherapy in patients with chronic hepatitis C.

Kobayashi T, Hige S, Terashita K, Nakai M, Horimoto H, Sho T, Nakanishi M, Ogawa K, Chuma M, Sakamoto N, Asaka M.

J Gastroenterol. 2012 Nov;47(11):1228-37. doi: 10.1007/s00535-012-0579-y. Epub 2012 Mar 30.

PMID:
22460221
10.

Association of ITPA gene polymorphisms and the risk of ribavirin-induced anemia in HIV/hepatitis C virus (HCV)-coinfected patients receiving HCV combination therapy.

Domingo P, Guardiola JM, Salazar J, Torres F, Mateo MG, Pacho C, Del Mar Gutierrez M, Lamarca K, Fontanet A, Martin J, Muñoz J, Vidal F, Baiget M.

Antimicrob Agents Chemother. 2012 Jun;56(6):2987-93. doi: 10.1128/AAC.06473-11. Epub 2012 Mar 19.

11.

Pivotal role of inosine triphosphate pyrophosphatase in maintaining genome stability and the prevention of apoptosis in human cells.

Menezes MR, Waisertreiger IS, Lopez-Bertoni H, Luo X, Pavlov YI.

PLoS One. 2012;7(2):e32313. doi: 10.1371/journal.pone.0032313. Epub 2012 Feb 27.

12.

Erythrocyte inosine triphosphatase activity is decreased in HIV-seropositive individuals.

Bierau J, Bakker JA, Schippers JA, Grashorn JA, Lindhout M, Lowe SH, Paulussen AD, Verbon A.

PLoS One. 2012;7(1):e30175. doi: 10.1371/journal.pone.0030175. Epub 2012 Jan 17.

13.

The effect of ITPA polymorphisms on the enzyme kinetic properties of human erythrocyte inosine triphosphatase toward its substrates ITP and 6-Thio-ITP.

Bakker JA, Lindhout M, Habets DD, van den Wijngaard A, Paulussen AD, Bierau J.

Nucleosides Nucleotides Nucleic Acids. 2011 Nov;30(11):839-49. doi: 10.1080/15257770.2011.606789.

PMID:
22060550
14.

Polymorphism of the inosine triphosphate pyrophosphatase gene predicts ribavirin-induced anemia in chronic hepatitis C patients.

Nishimura T, Osaki R, Shioya M, Imaeda H, Aomatsu T, Takeuchi T, Okumura Y, Fujiyama Y, Andoh A.

Mol Med Rep. 2012 Feb;5(2):517-20. doi: 10.3892/mmr.2011.659. Epub 2011 Nov 2.

PMID:
22052220
15.

Relationship between polymorphisms of the inosine triphosphatase gene and anaemia or outcome after treatment with pegylated interferon and ribavirin.

Kurosaki M, Tanaka Y, Tanaka K, Suzuki Y, Hoshioka Y, Tamaki N, Kato T, Yasui Y, Hosokawa T, Ueda K, Tsuchiya K, Kuzuya T, Nakanishi H, Itakura J, Takahashi Y, Asahina Y, Matsuura K, Sugauchi F, Enomoto N, Nishida N, Tokunaga K, Mizokami M, Izumi N.

Antivir Ther. 2011;16(5):685-94. doi: 10.3851/IMP1796.

PMID:
21817190
16.

Influence of ITPA polymorphisms on decreases of hemoglobin during treatment with pegylated interferon, ribavirin, and telaprevir.

Suzuki F, Suzuki Y, Akuta N, Sezaki H, Hirakawa M, Kawamura Y, Hosaka T, Kobayashi M, Saito S, Arase Y, Ikeda K, Kobayashi M, Chayama K, Kamatani N, Nakamura Y, Miyakawa Y, Kumada H.

Hepatology. 2011 Feb;53(2):415-21. doi: 10.1002/hep.24058. Epub 2011 Jan 18.

PMID:
21246582
17.

ITPA gene variant protects against anemia induced by pegylated interferon-α and ribavirin therapy for Japanese patients with chronic hepatitis C.

Sakamoto N, Tanaka Y, Nakagawa M, Yatsuhashi H, Nishiguchi S, Enomoto N, Azuma S, Nishimura-Sakurai Y, Kakinuma S, Nishida N, Tokunaga K, Honda M, Ito K, Mizokami M, Watanabe M.

Hepatol Res. 2010 Nov;40(11):1063-71. doi: 10.1111/j.1872-034X.2010.00741.x.

PMID:
20977565
18.

A role for ITPA variants in the clinical course of pulmonary Langerhans' cell histiocytosis?

Bakker JA, Bierau J, Drent M.

Eur Respir J. 2010 Sep;36(3):684-6. doi: 10.1183/09031936.00026610. No abstract available.

19.

ITPA protein, an enzyme that eliminates deaminated purine nucleoside triphosphates in cells.

Sakumi K, Abolhassani N, Behmanesh M, Iyama T, Tsuchimoto D, Nakabeppu Y.

Mutat Res. 2010 Nov 28;703(1):43-50. doi: 10.1016/j.mrgentox.2010.06.009. Epub 2010 Jun 22. Review.

PMID:
20601097
20.

Variants in the ITPA gene protect against ribavirin-induced hemolytic anemia and decrease the need for ribavirin dose reduction.

Thompson AJ, Fellay J, Patel K, Tillmann HL, Naggie S, Ge D, Urban TJ, Shianna KV, Muir AJ, Fried MW, Afdhal NH, Goldstein DB, McHutchison JG.

Gastroenterology. 2010 Oct;139(4):1181-9. doi: 10.1053/j.gastro.2010.06.016. Epub 2010 Jun 12.

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