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Items: 1 to 20 of 87


Addition of cetuximab to chemotherapy as first-line treatment for KRAS wild-type metastatic colorectal cancer: pooled analysis of the CRYSTAL and OPUS randomised clinical trials.

Bokemeyer C, Van Cutsem E, Rougier P, Ciardiello F, Heeger S, Schlichting M, Celik I, Köhne CH.

Eur J Cancer. 2012 Jul;48(10):1466-75. doi: 10.1016/j.ejca.2012.02.057. Epub 2012 Mar 23.


Gene expression profiling of peritoneal metastases from appendiceal and colon cancer demonstrates unique biologic signatures and predicts patient outcomes.

Levine EA, Blazer DG 3rd, Kim MK, Shen P, Stewart JH 4th, Guy C, Hsu DS.

J Am Coll Surg. 2012 Apr;214(4):599-606; discussion 606-7. doi: 10.1016/j.jamcollsurg.2011.12.028. Epub 2012 Feb 17.


Prostaglandin E2 promotes intestinal tumor growth via DNA methylation.

Xia D, Wang D, Kim SH, Katoh H, DuBois RN.

Nat Med. 2012 Jan 22;18(2):224-6. doi: 10.1038/nm.2608.


Cancer statistics, 2012.

Siegel R, Naishadham D, Jemal A.

CA Cancer J Clin. 2012 Jan-Feb;62(1):10-29. doi: 10.3322/caac.20138. Epub 2012 Jan 4.


Colon cancer.

Benson AB 3rd, Arnoletti JP, Bekaii-Saab T, Chan E, Chen YJ, Choti MA, Cooper HS, Dilawari RA, Engstrom PF, Enzinger PC, Fleshman JW Jr, Fuchs CS, Grem JL, Knol JA, Leong LA, Lin E, May KS, Mulcahy MF, Murphy K, Rohren E, Ryan DP, Saltz L, Sharma S, Shibata D, Skibber JM, Small W Jr, Sofocleous CT, Venook AP, Willett C; National Comprehensive Cancer Network..

J Natl Compr Canc Netw. 2011 Nov;9(11):1238-90. No abstract available.


Radiofrequency ablation vs hepatic resection for solitary colorectal liver metastasis: a meta-analysis.

Wu YZ, Li B, Wang T, Wang SJ, Zhou YM.

World J Gastroenterol. 2011 Sep 28;17(36):4143-8. doi: 10.3748/wjg.v17.i36.4143.


Comparison of adjuvant systemic chemotherapy with or without hepatic arterial infusional chemotherapy after hepatic resection for metastatic colorectal cancer.

House MG, Kemeny NE, Gönen M, Fong Y, Allen PJ, Paty PB, DeMatteo RP, Blumgart LH, Jarnagin WR, D'Angelica MI.

Ann Surg. 2011 Dec;254(6):851-6. doi: 10.1097/SLA.0b013e31822f4f88.


An update on the current and emerging targeted agents in metastatic colorectal cancer.

Chu E.

Clin Colorectal Cancer. 2012 Mar;11(1):1-13. doi: 10.1016/j.clcc.2011.05.005. Epub 2011 Jul 12. Review.


Four molecular subtypes of colorectal cancer and their precursor lesions.

Kang GH.

Arch Pathol Lab Med. 2011 Jun;135(6):698-703. doi: 10.1043/2010-0523-RA.1. Review.


DNA mismatch repair status and colon cancer recurrence and survival in clinical trials of 5-fluorouracil-based adjuvant therapy.

Sinicrope FA, Foster NR, Thibodeau SN, Marsoni S, Monges G, Labianca R, Kim GP, Yothers G, Allegra C, Moore MJ, Gallinger S, Sargent DJ.

J Natl Cancer Inst. 2011 Jun 8;103(11):863-75. doi: 10.1093/jnci/djr153. Epub 2011 May 19. Erratum in: J Natl Cancer Inst. 2011 Nov 2;103(21):1639. Kim, George P [added].


A perspective on cancer cell metastasis.

Chaffer CL, Weinberg RA.

Science. 2011 Mar 25;331(6024):1559-64. doi: 10.1126/science.1203543. Review.


Antiangiogenic therapy: impact on invasion, disease progression, and metastasis.

Ebos JM, Kerbel RS.

Nat Rev Clin Oncol. 2011 Mar 1;8(4):210-21. doi: 10.1038/nrclinonc.2011.21. Review. Erratum in: Nat Rev Clin Oncol. 2011;8(4):221. Nat Rev Clin Oncol. 2011 Jun;8(6):316.


Randomized phase II trial of adjuvant hepatic arterial infusion and systemic chemotherapy with or without bevacizumab in patients with resected hepatic metastases from colorectal cancer.

Kemeny NE, Jarnagin WR, Capanu M, Fong Y, Gewirtz AN, Dematteo RP, D'Angelica MI.

J Clin Oncol. 2011 Mar 1;29(7):884-9. doi: 10.1200/JCO.2010.32.5977. Epub 2010 Dec 28.


Lessons from the adjuvant bevacizumab trial on colon cancer: what next?

Van Cutsem E, Lambrechts D, Prenen H, Jain RK, Carmeliet P.

J Clin Oncol. 2011 Jan 1;29(1):1-4. doi: 10.1200/JCO.2010.32.2701. Epub 2010 Nov 29. No abstract available.


Association of KRAS p.G13D mutation with outcome in patients with chemotherapy-refractory metastatic colorectal cancer treated with cetuximab.

De Roock W, Jonker DJ, Di Nicolantonio F, Sartore-Bianchi A, Tu D, Siena S, Lamba S, Arena S, Frattini M, Piessevaux H, Van Cutsem E, O'Callaghan CJ, Khambata-Ford S, Zalcberg JR, Simes J, Karapetis CS, Bardelli A, Tejpar S.

JAMA. 2010 Oct 27;304(16):1812-20. doi: 10.1001/jama.2010.1535.


Phase III trial assessing bevacizumab in stages II and III carcinoma of the colon: results of NSABP protocol C-08.

Allegra CJ, Yothers G, O'Connell MJ, Sharif S, Petrelli NJ, Colangelo LH, Atkins JN, Seay TE, Fehrenbacher L, Goldberg RM, O'Reilly S, Chu L, Azar CA, Lopa S, Wolmark N.

J Clin Oncol. 2011 Jan 1;29(1):11-6. doi: 10.1200/JCO.2010.30.0855. Epub 2010 Oct 12.


Randomized, phase III trial of panitumumab with infusional fluorouracil, leucovorin, and oxaliplatin (FOLFOX4) versus FOLFOX4 alone as first-line treatment in patients with previously untreated metastatic colorectal cancer: the PRIME study.

Douillard JY, Siena S, Cassidy J, Tabernero J, Burkes R, Barugel M, Humblet Y, Bodoky G, Cunningham D, Jassem J, Rivera F, Kocákova I, Ruff P, Błasińska-Morawiec M, Šmakal M, Canon JL, Rother M, Oliner KS, Wolf M, Gansert J.

J Clin Oncol. 2010 Nov 1;28(31):4697-705. doi: 10.1200/JCO.2009.27.4860. Epub 2010 Oct 4.


Is there really a yin and yang to VEGF-targeted therapies?

Ellis LM, Reardon DA.

Lancet Oncol. 2010 Sep;11(9):809-11. doi: 10.1016/S1470-2045(10)70161-3. Epub 2010 Jul 13. No abstract available.


Phase III trial comparing protracted intravenous fluorouracil infusion alone or with yttrium-90 resin microspheres radioembolization for liver-limited metastatic colorectal cancer refractory to standard chemotherapy.

Hendlisz A, Van den Eynde M, Peeters M, Maleux G, Lambert B, Vannoote J, De Keukeleire K, Verslype C, Defreyne L, Van Cutsem E, Delatte P, Delaunoit T, Personeni N, Paesmans M, Van Laethem JL, Flamen P.

J Clin Oncol. 2010 Aug 10;28(23):3687-94. doi: 10.1200/JCO.2010.28.5643. Epub 2010 Jun 21.


The chromosomal instability pathway in colon cancer.

Pino MS, Chung DC.

Gastroenterology. 2010 Jun;138(6):2059-72. doi: 10.1053/j.gastro.2009.12.065. Review.

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