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Items: 1 to 20 of 28

1.

Ubiquitin-conjugating enzyme Ubc13 is a critical component of TNF receptor-associated factor (TRAF)-mediated inflammatory responses.

Fukushima T, Matsuzawa S, Kress CL, Bruey JM, Krajewska M, Lefebvre S, Zapata JM, Ronai Z, Reed JC.

Proc Natl Acad Sci U S A. 2007 Apr 10;104(15):6371-6. Epub 2007 Apr 2.

2.

Caspase-8 regulation by direct interaction with TRAF6 in T cell receptor-induced NF-kappaB activation.

Bidère N, Snow AL, Sakai K, Zheng L, Lenardo MJ.

Curr Biol. 2006 Aug 22;16(16):1666-71.

3.

Key function for the Ubc13 E2 ubiquitin-conjugating enzyme in immune receptor signaling.

Yamamoto M, Okamoto T, Takeda K, Sato S, Sanjo H, Uematsu S, Saitoh T, Yamamoto N, Sakurai H, Ishii KJ, Yamaoka S, Kawai T, Matsuura Y, Takeuchi O, Akira S.

Nat Immunol. 2006 Sep;7(9):962-70. Epub 2006 Jul 23.

PMID:
16862162
4.

Structural basis for non-covalent interaction between ubiquitin and the ubiquitin conjugating enzyme variant human MMS2.

Lewis MJ, Saltibus LF, Hau DD, Xiao W, Spyracopoulos L.

J Biomol NMR. 2006 Feb;34(2):89-100.

PMID:
16518696
5.

Chaperoned ubiquitylation--crystal structures of the CHIP U box E3 ubiquitin ligase and a CHIP-Ubc13-Uev1a complex.

Zhang M, Windheim M, Roe SM, Peggie M, Cohen P, Prodromou C, Pearl LH.

Mol Cell. 2005 Nov 23;20(4):525-38.

6.

Distinct regulation of Ubc13 functions by the two ubiquitin-conjugating enzyme variants Mms2 and Uev1A.

Andersen PL, Zhou H, Pastushok L, Moraes T, McKenna S, Ziola B, Ellison MJ, Dixit VM, Xiao W.

J Cell Biol. 2005 Aug 29;170(5):745-55.

7.

Ubiquitin signalling in the NF-kappaB pathway.

Chen ZJ.

Nat Cell Biol. 2005 Aug;7(8):758-65. Review.

8.

Mechanistic insight into osteoclast differentiation in osteoimmunology.

Takayanagi H.

J Mol Med (Berl). 2005 Mar;83(3):170-9. Epub 2005 Jan 26. Review.

PMID:
15776286
9.

TRAF-dependent association of protein kinase Tpl2/COT1 (MAP3K8) with CD40.

Chan H, Reed JC.

Biochem Biophys Res Commun. 2005 Mar 4;328(1):198-205.

PMID:
15670770
10.

TIFA activates IkappaB kinase (IKK) by promoting oligomerization and ubiquitination of TRAF6.

Ea CK, Sun L, Inoue J, Chen ZJ.

Proc Natl Acad Sci U S A. 2004 Oct 26;101(43):15318-23. Epub 2004 Oct 18.

11.

The TRAF6 RING finger domain mediates physical interaction with Ubc13.

Wooff J, Pastushok L, Hanna M, Fu Y, Xiao W.

FEBS Lett. 2004 May 21;566(1-3):229-33.

12.

The TRAF6 ubiquitin ligase and TAK1 kinase mediate IKK activation by BCL10 and MALT1 in T lymphocytes.

Sun L, Deng L, Ea CK, Xia ZP, Chen ZJ.

Mol Cell. 2004 May 7;14(3):289-301.

13.

A conserved catalytic residue in the ubiquitin-conjugating enzyme family.

Wu PY, Hanlon M, Eddins M, Tsui C, Rogers RS, Jensen JP, Matunis MJ, Weissman AM, Wolberger C, Pickart CM.

EMBO J. 2003 Oct 1;22(19):5241-50. Erratum in: EMBO J. 2007 Sep 5;26(17):4051. Weisman, Allan M [corrected to Weissman, Allan M]. EMBO J. 2004 Dec 8;23(24):4876. Weissman, Allan M [corrected to Weisman, Allan M].

15.

An NMR-based model of the ubiquitin-bound human ubiquitin conjugation complex Mms2.Ubc13. The structural basis for lysine 63 chain catalysis.

McKenna S, Moraes T, Pastushok L, Ptak C, Xiao W, Spyracopoulos L, Ellison MJ.

J Biol Chem. 2003 Apr 11;278(15):13151-8. Epub 2003 Feb 4.

16.

NF-kappaB at the crossroads of life and death.

Karin M, Lin A.

Nat Immunol. 2002 Mar;3(3):221-7. Review.

PMID:
11875461
17.

Crystal structure of the human ubiquitin conjugating enzyme complex, hMms2-hUbc13.

Moraes TF, Edwards RA, McKenna S, Pastushok L, Xiao W, Glover JN, Ellison MJ.

Nat Struct Biol. 2001 Aug;8(8):669-73.

PMID:
11473255
18.

TAK1 is a ubiquitin-dependent kinase of MKK and IKK.

Wang C, Deng L, Hong M, Akkaraju GR, Inoue J, Chen ZJ.

Nature. 2001 Jul 19;412(6844):346-51.

PMID:
11460167
19.

Molecular insights into polyubiquitin chain assembly: crystal structure of the Mms2/Ubc13 heterodimer.

VanDemark AP, Hofmann RM, Tsui C, Pickart CM, Wolberger C.

Cell. 2001 Jun 15;105(6):711-20.

20.

Tumor necrosis factor receptor-associated factor (TRAF)2 represses the T helper cell type 2 response through interaction with NFAT-interacting protein (NIP45).

Lieberson R, Mowen KA, McBride KD, Leautaud V, Zhang X, Suh WK, Wu L, Glimcher LH.

J Exp Med. 2001 Jul 2;194(1):89-98.

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