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Training translators for smart drug discovery.

Skarke C, FitzGerald GA.

Sci Transl Med. 2010 Apr 7;2(26):26cm12. doi: 10.1126/scitranslmed.3000890.


A TOMM40 variable-length polymorphism predicts the age of late-onset Alzheimer's disease.

Roses AD, Lutz MW, Amrine-Madsen H, Saunders AM, Crenshaw DG, Sundseth SS, Huentelman MJ, Welsh-Bohmer KA, Reiman EM.

Pharmacogenomics J. 2010 Oct;10(5):375-84. doi: 10.1038/tpj.2009.69. Epub 2009 Dec 22.


Utility of adiponectin as a biomarker predictive of glycemic efficacy is demonstrated by collaborative pooling of data from clinical trials conducted by multiple sponsors.

Wagner JA, Wright EC, Ennis MM, Prince M, Kochan J, Nunez DJ, Schneider B, Wang MD, Chen Y, Ghosh S, Musser BJ, Vassileva MT.

Clin Pharmacol Ther. 2009 Dec;86(6):619-25. doi: 10.1038/clpt.2009.88. Epub 2009 Jun 24.


Mouse population-guided resequencing reveals that variants in CD44 contribute to acetaminophen-induced liver injury in humans.

Harrill AH, Watkins PB, Su S, Ross PK, Harbourt DE, Stylianou IM, Boorman GA, Russo MW, Sackler RS, Harris SC, Smith PC, Tennant R, Bogue M, Paigen K, Harris C, Contractor T, Wiltshire T, Rusyn I, Threadgill DW.

Genome Res. 2009 Sep;19(9):1507-15. doi: 10.1101/gr.090241.108. Epub 2009 May 5.

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