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Items: 6

1.

Selective and brain penetrant neuropeptide y y2 receptor antagonists discovered by whole-cell high-throughput screening.

Brothers SP, Saldanha SA, Spicer TP, Cameron M, Mercer BA, Chase P, McDonald P, Wahlestedt C, Hodder PS.

Mol Pharmacol. 2010 Jan;77(1):46-57. doi: 10.1124/mol.109.058677.

2.

Characterization of N-(1-Acetyl-2,3-dihydro-1H-indol-6-yl)-3-(3-cyano-phenyl)-N-[1-(2-cyclopentyl-ethyl)-piperidin-4yl]acrylamide (JNJ-5207787), a small molecule antagonist of the neuropeptide Y Y2 receptor.

Bonaventure P, Nepomuceno D, Mazur C, Lord B, Rudolph DA, Jablonowski JA, Carruthers NI, Lovenberg TW.

J Pharmacol Exp Ther. 2004 Mar;308(3):1130-7.

3.
4.

Prediction of intestinal permeability.

Egan WJ, Lauri G.

Adv Drug Deliv Rev. 2002 Mar 31;54(3):273-89. Review.

PMID:
11922948
5.

Estimation of aqueous solubility of chemical compounds using E-state indices.

Tetko IV, Tanchuk VY, Kasheva TN, Villa AE.

J Chem Inf Comput Sci. 2001 Nov-Dec;41(6):1488-93.

PMID:
11749573
6.

Prediction of drug absorption using multivariate statistics.

Egan WJ, Merz KM Jr, Baldwin JJ.

J Med Chem. 2000 Oct 19;43(21):3867-77.

PMID:
11052792

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