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Items: 11

1.

New positron emission tomography tracer [(11)C]carvedilol reveals P-glycoprotein modulation kinetics.

Bart J, Dijkers EC, Wegman TD, de Vries EG, van der Graaf WT, Groen HJ, Vaalburg W, Willemsen AT, Hendrikse NH.

Br J Pharmacol. 2005 Aug;145(8):1045-51.

2.

Synthesis and evaluation of radiolabeled antagonists for imaging of beta-adrenoceptors in the brain with PET.

Doze P, Elsinga PH, Maas B, Van Waarde A, Wegman T, Vaalburg W.

Neurochem Int. 2002 Feb;40(2):145-55.

PMID:
11738481
3.

Increase in doxorubicin cytotoxicity by carvedilol inhibition of P-glycoprotein activity.

Jonsson O, Behnam-Motlagh P, Persson M, Henriksson R, Grankvist K.

Biochem Pharmacol. 1999 Dec 1;58(11):1801-6.

PMID:
10571255
4.

Metabolism of carvedilol in dogs, rats, and mice.

Schaefer WH, Politowski J, Hwang B, Dixon F Jr, Goalwin A, Gutzait L, Anderson K, DeBrosse C, Bean M, Rhodes GR.

Drug Metab Dispos. 1998 Oct;26(10):958-69.

5.

Modulation of doxorubicin concentration by cyclosporin A in brain and testicular barrier tissues expressing P-glycoprotein in rats.

Hughes CS, Vaden SL, Manaugh CA, Price GS, Hudson LC.

J Neurooncol. 1998 Mar;37(1):45-54.

PMID:
9525837
6.

Full blockade of intestinal P-glycoprotein and extensive inhibition of blood-brain barrier P-glycoprotein by oral treatment of mice with PSC833.

Mayer U, Wagenaar E, Dorobek B, Beijnen JH, Borst P, Schinkel AH.

J Clin Invest. 1997 Nov 15;100(10):2430-6.

7.

Biochemistry of multidrug resistance mediated by the multidrug transporter.

Gottesman MM, Pastan I.

Annu Rev Biochem. 1993;62:385-427. Review. No abstract available.

PMID:
8102521
8.

Characterization of multidrug resistance P-glycoprotein transport function with an organotechnetium cation.

Piwnica-Worms D, Rao VV, Kronauge JF, Croop JM.

Biochemistry. 1995 Sep 26;34(38):12210-20.

PMID:
7547962
9.

The biochemistry of P-glycoprotein-mediated multidrug resistance.

Endicott JA, Ling V.

Annu Rev Biochem. 1989;58:137-71. Review. No abstract available.

PMID:
2570548
10.

Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues.

Thiebaut F, Tsuruo T, Hamada H, Gottesman MM, Pastan I, Willingham MC.

Proc Natl Acad Sci U S A. 1987 Nov;84(21):7735-8.

11.

Expression of a multidrug-resistance gene in human tumors and tissues.

Fojo AT, Ueda K, Slamon DJ, Poplack DG, Gottesman MM, Pastan I.

Proc Natl Acad Sci U S A. 1987 Jan;84(1):265-9.

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