Format

Send to

Choose Destination
See comment in PubMed Commons below
Exp Parasitol. 1999 Feb;91(2):115-8.

Plasmodium falciparum: enhanced gametocyte formation in vitro in reticulocyte-rich blood.

Author information

  • 1Rockefeller Univerisity, New York, New York 10021, USA.

Abstract

Concentrates of late stage parasites of the gametocyte-forming clone HB-3 were mixed with blood rich in reticulocytes from anemic patients, or with normal control blood, and kept under culture conditions for 4 days. Significantly more gametocytes were always formed in the reticulocyte-rich blood than in the control. This was true whether the anemic blood supported a larger asexual parasitemia than the control, or a lower one, or the same and without regard to the cause of the anemia. Gametocytes as a percentage of asexual forms were up to 10 times higher in reticulocyte-rich blood than in normal blood.

PMID:
9990338
DOI:
10.1006/expr.1998.4347
[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Support Center