Format

Send to

Choose Destination
Med Mycol. 1998;36 Suppl 1:95-105.

Antibody and/or cell-mediated immunity, protective mechanisms in fungal disease: an ongoing dilemma or an unnecessary dispute?

Author information

1
Albert Einstein College of Medicine, Bronx, New York, USA.

Abstract

Historically there has been controversy on the relative importance of antibody- and cell-mediated immune responses in the protection against fungal pathogens. The controversy was fuelled by the difficulties encountered in obtaining consistent results with polyclonal antibody experiments and I inducing long-lasting immune protection by vaccinations with induce stron cell-mediated responses. Recent studies indicate that both antibody- and cell-mediated immune responses can contribute to host protection against Candida albicans and C. neoformans. At the present time the major issue is not the relative importance of antibody- and cell-mediated immune responses but rather, the mechanisms by which the two arms of the immune system function and cooperate.

PMID:
9988497
[Indexed for MEDLINE]

Supplemental Content

Loading ...
Support Center