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Ophthalmology. 1999 Feb;106(2):290-4.

Choroidal tuberculosis diagnosed by polymerase chain reaction. A clinicopathologic case report.

Author information

1
Department of Ophthalmology, Queen's Medical Centre, Nottingham, England.

Abstract

PURPOSE:

To show the use of the polymerase chain reaction (PCR) in a granulomatous choroidal lesion to support a diagnosis of tuberculosis.

DESIGN:

Observational case report.

TESTING:

Nucleic acid target amplification of a choroidal specimen using PCR for detection of Mycobacterium tuberculosis was tested.

MAIN OUTCOME MEASURES:

Positive nucleic acid target amplification for M. tuberculosis in the ocular sample was measured.

RESULTS:

PCR was positive for M. tuberculosis with appropriate negative controls.

CONCLUSIONS:

PCR was thought to be a useful supportive technique in the diagnosis of choroidal tuberculosis.

PMID:
9951479
DOI:
10.1016/S0161-6420(99)90068-4
[Indexed for MEDLINE]

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