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Eur J Immunogenet. 1998 Dec;25(6):419-20.

Two novel biallelic polymorphisms in the IL-2 gene.

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National Blood Service, North London Centre, UK.


We have detected two novel single nucleotide polymorphisms in the IL-2 gene, at positions -330 and +166 relative to the transcription start site. The +166 change occurs within the leader peptide and does not affect amino acid sequence. The -330 polymorphism has two common alleles, making it an ideal marker for genetic association studies.

[Indexed for MEDLINE]

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