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Bioorg Med Chem Lett. 1998 Dec 15;8(24):3475-8.

Anti-HIV coumarins from Calophyllum seed oil.

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1
Université de Sherbrooke, Département de Chimie, Qc., Canada.

Abstract

The seeds of Calophyllum cerasiferum Vesque (Family-Clusiaceae), and Calophyllum inophyllum Linn. (Family-Clusiaceae) contain several known coumarins, among which were the potent HIV reverse transcriptase inhibitors costatolide and inophyllum P. Calophyllum cerasiferum contained (-)-calanolide B as its major coumarin constituent in significant amount and thus constitute a renewable source of this compound.

PMID:
9934455
[Indexed for MEDLINE]

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