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Annu Rev Genet. 1998;32:521-45.

Early patterning of the C. elegans embryo.

Author information

1
Section of Molecular and Cellular Biology, University of California, Davis 95616, USA. lsrose@ucdavis.edu

Abstract

Studies of about 20 maternally expressed genes are providing an understanding of mechanisms of patterning and cell-fate determination in the early Caenorhabditis elegans embryo. The analyses have revealed that fates of the early blastomeres are specified by a combination of intrinsically asymmetric cell divisions and two types of cell-cell interactions: inductions and polarizing interactions. In this review we summarize the current level of understanding of the molecular mechanisms underlying these processes in the specification of cell fates in the pregastrulation embryo.

PMID:
9928490
DOI:
10.1146/annurev.genet.32.1.521
[Indexed for MEDLINE]

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