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J Am Acad Dermatol. 1999 Jan;40(1):73-6.

Long-term results of isotretinoin in the treatment of 68 patients with hidradenitis suppurativa.

Author information

1
Department of Dermatology, Deventer Hospital, The Netherlands.

Abstract

BACKGROUND:

Oral isotretinoin has been used to treat mild to severe hidradenitis suppurativa (HS).

OBJECTIVE:

We reviewed the results of low-dose isotretinoin for 4 to 6 months in the treatment of 68 patients with HS.

METHODS:

This is a retrospective study. Data are presented in terms of response rate, long-term follow-up, and the relation between response rate and severity.

RESULTS:

In 16 patients (23.5%), the condition completely cleared during initial therapy and 11 patients (16.2%) maintained their improvement during the follow-up period. Treatment was more successful in the milder forms of HS.

CONCLUSION:

Monotherapy with isotretinoin for patients with HS usually has a limited therapeutic effect.

PMID:
9922015
DOI:
10.1016/s0190-9622(99)70530-x
[Indexed for MEDLINE]

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