Format

Send to

Choose Destination
See comment in PubMed Commons below
Obstet Gynecol. 1999 Jan;93(1):135-9.

High-resolution imaging of gynecologic neoplasms using optical coherence tomography.

Author information

  • 1Department of Electrical Engineering and Computer Science, Massachusetts Institute of Technology, Cambridge 02139, USA. cpitris@mit.edu

Abstract

BACKGROUND:

A modality capable of imaging the female reproductive tract, at or near the cellular level, could lead to the detection of diseases at earlier stages than currently possible. Optical coherence tomography achieves high resolutions in the cellular range (4-20 microm) and could accomplish that level of detection.

METHOD:

Optical coherence tomography imaging of gynecologic tissue was studied in vitro on normal and neoplastic human cervical and uterine tissue.

EXPERIENCE:

The structures of the normal ectocervix and endocervix, including epithelium, basal membrane, and glands, were identified clearly. These findings were compared with changes associated with carcinoma in situ and invasive carcinoma. The optical coherence tomography images of the uterus also showed changes between microstructural features of normal tissue and endometrial adenocarcinoma.

CONCLUSION:

Optical coherence tomography of tissue microstructures showed potential for powerful, minimally invasive assessment of the female reproductive tract at a resolution greater than any current clinical imaging method.

PMID:
9916971
[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Loading ...
    Write to the Help Desk