A Caenorhabditis elegans homeobox gene expressed in the male tail, a link between pattern formation and sexual dimorphism?

Dev Genes Evol. 1999 Jan;209(1):59-62. doi: 10.1007/s004270050227.

Abstract

ceh-7 is a small Caenorhabditis elegans homeobox gene. We have shown that this gene is transcribed. Examination of the expression pattern of ceh-7 using reporter constructs revealed that it is expressed in a few cells of the male tail, which form a ring around the rectum. The most posterior member of the C. elegans Hox cluster, egl-5, an Abd-B homologue, has previously been shown to be required for the proper development of several blast cells in the male tail. We have examined the expression of ceh-7 in mutant backgrounds of egl-5 and also mab-5, an Antp/Ubx/Abd-A homologue. We find that ceh-7 is not expressed in egl-5 mutants, but is still expressed in mab-5 mutants.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amino Acid Sequence
  • Animals
  • Base Sequence
  • Caenorhabditis elegans / embryology
  • Caenorhabditis elegans / genetics*
  • Caenorhabditis elegans Proteins*
  • Cloning, Molecular
  • Gene Expression Regulation, Developmental
  • Genes, Helminth*
  • Genes, Homeobox / physiology*
  • Green Fluorescent Proteins
  • Homeodomain Proteins / genetics*
  • Homeodomain Proteins / metabolism
  • Indicators and Reagents
  • Luminescent Proteins
  • Male
  • Microscopy, Fluorescence
  • Molecular Sequence Data
  • Sex Determination Processes*
  • Tail / embryology
  • Tail / physiology*
  • Tissue Distribution
  • Transcription Factors / genetics*

Substances

  • Caenorhabditis elegans Proteins
  • Homeodomain Proteins
  • Indicators and Reagents
  • Luminescent Proteins
  • Mab-5 protein, C elegans
  • Transcription Factors
  • ceh-7 protein, C elegans
  • Green Fluorescent Proteins