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Curr Opin Struct Biol. 1998 Dec;8(6):713-9.

The structure, catalytic mechanism and regulation of adenylyl cyclase.

Author information

1
Howard Hughes Medical Institute Department of Biochemistry University of Texas Southwestern Medical Center 5323 Harry Hines Boulevard Dallas TX 75235-9050 USA. tesmer@chop.swmed.edu

Abstract

The recent structure determinations of the mammalian effector enzyme adenylyl cyclase reveal the structure of its catalytic core, provide new insights into its catalytic mechanism and suggest how diverse signaling molecules regulate its activity.

PMID:
9914249
DOI:
10.1016/s0959-440x(98)80090-0
[Indexed for MEDLINE]

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