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Curr Opin Neurobiol. 1998 Dec;8(6):791-9.

The genetic and molecular mechanisms of motor neuron disease.

Author information

1
Department of Pathology, Division of Neuropathology, The Johns Hopkins University School of Medicine, 720 Rutland Avenue, Baltimore, Maryland 21205-2196, USA. pcwong@welchlink.welch.jhu.edu

Abstract

Significant progress has been made in the identification of genes and chromosomal loci associated with several types of motor neuron disease. Of particular interest is recent work on the pathogenic mechanisms underlying these diseases, especially studies in in vitro model systems and in transgenic and gene-targeted mice.

PMID:
9914243
DOI:
10.1016/s0959-4388(98)80123-2
[Indexed for MEDLINE]

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