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Curr Opin Immunol. 1998 Dec;10(6):718-25.

Susceptibility to lupus nephritis in the NZB/W model system.

Author information

1
Center for Mammalian Genetics Department of Immunology, Pathology, and Laboratory Medicine University of Florida Gainesville FL 32610-0275 USA. morel@ufl.edu

Abstract

Advances in genetic mapping have resulted in the identification of multiple lupus susceptibility loci in the NZB/W mouse model. The analysis of congenic strains carrying these loci is now providing functional data on their role in lupus pathogenesis and is paving the way to the identification of the susceptibility genes and their molecular characterization.

PMID:
9914223
DOI:
10.1016/s0952-7915(98)80094-0
[Indexed for MEDLINE]

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