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Curr Opin Cell Biol. 1998 Dec;10(6):749-58.

Mitotic DNA damage and replication checkpoints in yeast.

Author information

1
The Scripps Research Institute 10550 Torrey Pines Road La Jolla CA 92037 USA.

Abstract

Studies of the genetics of G2/M checkpoints in budding and fission yeasts have produced many of the defining concepts of checkpoint biology. Recent progress in the biochemistry of the checkpoint gene products is adding a mechanistic understanding to our models and identifying the components of the normal cell cycle machinery that are targeted by checkpoints.

PMID:
9914174
PMCID:
PMC2864141
[Indexed for MEDLINE]
Free PMC Article

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