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Am J Kidney Dis. 1998 Dec;32(6 Suppl 4):S113-7.

Role of the systemic inflammatory response syndrome in the development of protein-calorie malnutrition in ESRD.

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Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA.


Chronic activation of the systemic inflammatory response is a common and unifying factor in many end-stage illnesses, particularly end-stage renal disease. Protein-calorie malnutrition and hypoalbuminemia, which are prominent features of end-stage renal disease, develop as a consequence of this syndrome. Recognition of this relationship can assist in the development of new approaches to the successful management of protein-calorie malnutrition developing in the course of end-stage renal disease.

[Indexed for MEDLINE]

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