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Ontogenez. 1998 Sep-Oct;29(5):323-34.

[Multiple role of hedgehog genes in vertebrates: data from analysis of mutations].

[Article in Russian]

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  • 1Institute of Molecular Agrobiology, Singapore.


Hedgehog (hh) gene has been discovered in Drosophila as result of the now famous screen for embryonic mutants in Drosophila performed by Dr. Christianne Nusslein-Volhard and her Ph.D. student Eric Wieschaus in 1980 in Tubingen, Germany (Nusslein-Volhard and Wieschaus, 1980). Due to recognition of the impact of these mutants onto contemporary developmental biology these scientists obtained a Nobel Prize in 1995. By that time it become obvious that the history of hh studies represents one of the most interesting chapters of developmental biology.

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