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Nervenarzt. 1998 Dec;69(12):1074-82.

[Noninvasive intermittent self-ventilation as a palliative measure in amyotrophic lateral sclerosis].

[Article in German]

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Neurologische Klinik, Klinikum Grosshadern, Ludwig-Maximilians-Universit√§t, M√ľnchen.


Almost all patients with amyotrophic lateral sclerosis (ALS) experience symptoms of nocturnal hypoventilation during the course of the illness. These symptoms can develop years before death and may severely affect quality of life. Non-invasive intermittent home mechanical ventilation (HMV) via mask is a possible palliative measure for these symptoms, which is not often used in Germany. We report on our experience with HMV in 24 patients with ALS. Our data show a good palliative effect in 17 of 24 treated patients. Severe complications did not occur. The mean ventilation time at present is 14 months. Available options and their consequences need to be discussed in detail with patients and relatives before HMV is initiated.

[Indexed for MEDLINE]

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