Send to

Choose Destination
See comment in PubMed Commons below
Biometrics. 1998 Dec;54(4):1638-44.

The analysis of correlated panel data using a continuous-time Markov model.

Author information

  • 1Epidemiology and Biostatistics Program, Institute of Environmental Medicine, New York University Medical Center, New York 10010, USA.


We consider the analysis of correlated panel data in which two or more correlated multistate processes are periodically observed on each individual and the exact transition times between states are unknown. We describe a procedure that models each process marginally under a time-homogeneous Markov model allowing for covariates. The resulting estimators are shown to be asymptotically jointly normal with a covariance matrix that can be consistently estimated. Simultaneous inference procedures are also proposed. Methods are illustrated using data from an AIDS clinical trial to compare the toxic effects of two treatments on two hematologic variables, hemoglobin and absolute neutrophil count.

[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Loading ...
    Support Center