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J Virol. 1999 Feb;73(2):1235-8.

Detection and sequence analysis of hepatitis B virus integration in peripheral blood mononuclear cells.

Author information

1
Division of Gastroenterology and Hepatology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213, USA. Laskus@pitt.edu

Abstract

A PCR-based technique was used to detect hepatitis B virus (HBV) integration in peripheral blood mononuclear cells from patients with chronic hepatitis B. Integrated HBV DNA sequences, with virus-cell junctions located in the cohesive region between direct repeat 1 (DR1) and DR2, were found in 2 of 10 studied patients.

PMID:
9882326
PMCID:
PMC103945
[Indexed for MEDLINE]
Free PMC Article

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