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Am Heart J. 1999 Jan;137(1):126-33.

Cardiovascular responses to exercise in children and adolescents with myocardial dysfunction.

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1
Department of Pediatrics, Baystate Medical Center, Springfield, Mass 01199, USA.

Abstract

OBJECTIVES:

The objective of this study was to understand the expected hemodynamic responses to exercise in children and adolescents with myocardial dysfunction.

METHODS AND RESULTS:

With the use of Doppler and M-mode echocardiography, cardiovascular changes during maximal semisupine exercise in 11 patients (7 to 17 years old) with myocardial dysfunction were compared with those of a healthy control group (n = 11). Endurance fitness and mean values for maximal cardiac index, stroke index, heart rate, peak aortic velocity, and left ventricular shortening fraction were all significantly lower in the patients (P <.05). Stroke volume rose at the onset of exercise in both groups; whereas values were subsequently stable in the control subjects, stroke volume declined at high-intensity exercise in the patients.

CONCLUSIONS:

These findings imply that augmented myocardial contractility is necessary to sustain stroke volume during exercise. Moreover, the results suggest that pattern of stroke volume response to exercise may serve as a useful marker of myocardial function in children with heart disease.

PMID:
9878945
[Indexed for MEDLINE]
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