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Bioorg Med Chem Lett. 1998 Jul 7;8(13):1639-42.

Adenosine deaminase inhibitors. Synthesis and biological evaluation of aralkyladenines (ARADS).

Author information

1
Department of Biomedical Sciences, University of Rhode Island, Kingston 02881-0809, USA.

Abstract

Several 9-aralkyladenines have been prepared and their ADA inhibitory activity was determined. A minimum of two carbon atoms separating the aromatic ring from the adenine-bearing carbon (C3') was found essential for potent activity.

PMID:
9873405
DOI:
10.1016/s0960-894x(98)00291-1
[Indexed for MEDLINE]

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