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Bioorg Med Chem Lett. 1998 Apr 7;8(7):781-6.

Amygdalin binds to the CD4 receptor as suggested from molecular modeling studies.

Author information

1
Dept. d'Enginyeria Quimica, Universitat Politecnica de Catalunya, ETSEIB, Barcelona, Spain.

Abstract

The geometrical features of the proposed bioactive conformation of peptide T assessed by computational methods in a previous study, together with available structure-activity studies on peptide T, led us to propose a pharmacophore for the CD4-peptide T interaction. Subsequent, data base searching permitted us to identify amygdalin as a peptide T peptidomimetic.

PMID:
9871541
[Indexed for MEDLINE]

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