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Curr Opin Nephrol Hypertens. 1998 Nov;7(6):691-4.

Protocol biopsies in renal transplantation: research tool or clinically useful?

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Department of Medicine, Health Sciences Centre, Winnipeg, Manitoba, Canada.


Early protocol biopsies of stable, well functioning renal allografts reveal a high prevalence of clinically unsuspected acute and chronic pathology. It is becoming increasingly apparent that these histopathological findings are both pathogenic and predictive of long-term allograft outcome. Therefore, protocol biopsies may be required for optimal post-transplant surveillance until non-invasive methods to detect allograft inflammation are developed.

[Indexed for MEDLINE]

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