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Genetika. 1976;12(4):41-6.

[Genetic analysis of the rate of sexual maturation in female mice].

[Article in Russian]


In studies of the female progeny of complete diallel crossing of BALB/c, C3H/He, C57BL/6, AKR/J mice a considerable influence of the genotype on the variability for such characters as the age of the vagina opening and the weight at that time, the age of the first oestrus and the weight at that time, the weight at 6 weeks was observed. The analysis of the effects of the general and specific combining ability demonstrated that non-additive gene effects play the major role in the determination of the day the begining oestral activity and the weight on this day. The age and the weight on the day of vaginal opening are inherited additively. It is demonstrated that the females of BALB/c and C3H/He (mammary tumour susceptible strains) are characterized by higher rate of sexual maturation than those of C57BL/6 and AKR/J in which the tumours of this localization are rare.

[Indexed for MEDLINE]

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