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Structure. 1998 Dec 15;6(12):1487-91.

Springs and zippers: coiled coils in SNARE-mediated membrane fusion.

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1
Department of Biochemistry Beckman B437 Stanford University Stanford CA 94305 USA. harbury@cmgm.stanford.edu

Abstract

A conserved molecular machinery based on SNARE proteins catalyzes most, if not all, cellular membrane fusion events. A flurry of recent biophysical studies have established a detailed molecular picture of the core SNARE complex. Structural and biochemical analysis of the SNARE machinery is rapidly advancing our understanding of the specificity, regulation and protein catalysis of membrane fusion.

PMID:
9862813
[Indexed for MEDLINE]
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