Refined chromosomal localization of the putative tumor suppressor gene TP73

C Lo Cunsolo; I Casciano; B Banelli; G P Tonini; M Romani

doi:10.1159/000015099

Refined chromosomal localization of the putative tumor suppressor gene TP73

Cytogenet Cell Genet. 1998;82(3-4):199-201. doi: 10.1159/000015099.

Authors

C Lo Cunsolo¹, I Casciano, B Banelli, G P Tonini, M Romani

Affiliation

¹ Solid Tumor Biology Unit, Advanced Biotechnology Center (CBA), Genova (Italy).

PMID: 9858816
DOI: 10.1159/000015099

Abstract

We report the refined chromosomal localization of the putative tumor suppressor gene TP73 (alias p73) within the genomic region between the anonymous loci D1Z2 and D1S47. The region measures less than 6 Mb and covers a genetic distance of 16 cM. The present mapping considerably restricts the previous cytogenetic localization of TP73.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Brain Neoplasms / genetics*
Chromosome Mapping*
DNA, Neoplasm / analysis
DNA-Binding Proteins / genetics*
Gene Deletion
Genes, Tumor Suppressor / genetics*
Genetic Markers
Humans
In Situ Hybridization, Fluorescence
Neuroblastoma / genetics*
Nuclear Proteins / genetics*
Tumor Cells, Cultured
Tumor Protein p73
Tumor Suppressor Proteins

Substances

DNA, Neoplasm
DNA-Binding Proteins
Genetic Markers
Nuclear Proteins
TP73 protein, human
Tumor Protein p73
Tumor Suppressor Proteins