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Neuroreport. 1998 Nov 16;9(16):3571-5.

Alteration of digital representations in somatosensory cortex in focal hand dystonia.

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Department of Psychology, University of Konstanz, Germany.


Focal hand dystonia involves a loss of motor control of one or more digits; it is associated with the repetitive, synchronous movements of the digits made by musicians over periods of many years. Magnetic source imaging revealed that there is a smaller distance (fusion) between the representations of the digits in somatosensory cortex for the affected hand of dystonic musicians than for the hands of non-musician control subjects. The data suggest that use-dependent susceptibility to digital representation fusion in cortex may be involved in the etiology of focal dystonia. A successful therapy for the condition has been developed based on this consideration.

[Indexed for MEDLINE]

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