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Trends Biochem Sci. 1998 Nov;23(11):429-33.

The structural and mechanochemical cycle of kinesin.

Author information

1
Max Planck Unit for Structural Molecular Biology, Hamburg, Germany. mand@mpasmb.desy.de

Abstract

Kinesin is a microtubule-based motor protein that pulls vesicles or organelles towards the plus end of microtubules. Structural changes in the protein that drive motility are coupled to ATP binding and hydrolysis. Here, we attempt to integrate recent structural and kinetic results into a picture of the mechanochemical cycle of kinesin.

PMID:
9852761
DOI:
10.1016/s0968-0004(98)01278-x
[Indexed for MEDLINE]

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