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2016 | 1 |
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A new protein conjugation system in human. The counterpart of the yeast Apg12p conjugation system essential for autophagy.
J Biol Chem. 1998 Dec 18;273(51):33889-92. doi: 10.1074/jbc.273.51.33889.
J Biol Chem. 1998.
PMID: 9852036
Free article.
The human homolog of Saccharomyces cerevisiae Apg7p is a Protein-activating enzyme for multiple substrates including human Apg12p, GATE-16, GABARAP, and MAP-LC3.
Tanida I, Tanida-Miyake E, Ueno T, Kominami E.
Tanida I, et al.
J Biol Chem. 2001 Jan 19;276(3):1701-6. doi: 10.1074/jbc.C000752200. Epub 2000 Nov 28.
J Biol Chem. 2001.
PMID: 11096062
Free article.
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Human Apg3p/Aut1p homologue is an authentic E2 enzyme for multiple substrates, GATE-16, GABARAP, and MAP-LC3, and facilitates the conjugation of hApg12p to hApg5p.
Tanida I, Tanida-Miyake E, Komatsu M, Ueno T, Kominami E.
Tanida I, et al.
J Biol Chem. 2002 Apr 19;277(16):13739-44. doi: 10.1074/jbc.M200385200. Epub 2002 Feb 1.
J Biol Chem. 2002.
PMID: 11825910
Free article.
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Network organization of the human autophagy system.
Behrends C, Sowa ME, Gygi SP, Harper JW.
Behrends C, et al.
Nature. 2010 Jul 1;466(7302):68-76. doi: 10.1038/nature09204. Epub 2010 Jun 20.
Nature. 2010.
PMID: 20562859
Free PMC article.
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Structure of the human ATG12~ATG5 conjugate required for LC3 lipidation in autophagy.
Otomo C, Metlagel Z, Takaesu G, Otomo T.
Otomo C, et al.
Nat Struct Mol Biol. 2013 Jan;20(1):59-66. doi: 10.1038/nsmb.2431. Epub 2012 Dec 2.
Nat Struct Mol Biol. 2013.
PMID: 23202584
Free PMC article.
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A proteome-scale map of the human interactome network.
Rolland T, Taşan M, Charloteaux B, Pevzner SJ, Zhong Q, Sahni N, Yi S, Lemmens I, Fontanillo C, Mosca R, Kamburov A, Ghiassian SD, Yang X, Ghamsari L, Balcha D, Begg BE, Braun P, Brehme M, Broly MP, Carvunis AR, Convery-Zupan D, Corominas R, Coulombe-Huntington J, Dann E, Dreze M, Dricot A, Fan C, Franzosa E, Gebreab F, Gutierrez BJ, Hardy MF, Jin M, Kang S, Kiros R, Lin GN, Luck K, MacWilliams A, Menche J, Murray RR, Palagi A, Poulin MM, Rambout X, Rasla J, Reichert P, Romero V, Ruyssinck E, Sahalie JM, Scholz A, Shah AA, Sharma A, Shen Y, Spirohn K, Tam S, Tejeda AO, Wanamaker SA, Twizere JC, Vega K, Walsh J, Cusick ME, Xia Y, Barabási AL, Iakoucheva LM, Aloy P, De Las Rivas J, Tavernier J, Calderwood MA, Hill DE, Hao T, Roth FP, Vidal M.
Rolland T, et al.
Cell. 2014 Nov 20;159(5):1212-1226. doi: 10.1016/j.cell.2014.10.050.
Cell. 2014.
PMID: 25416956
Free PMC article.
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Mutation in ATG5 reduces autophagy and leads to ataxia with developmental delay.
Kim M, Sandford E, Gatica D, Qiu Y, Liu X, Zheng Y, Schulman BA, Xu J, Semple I, Ro SH, Kim B, Mavioglu RN, Tolun A, Jipa A, Takats S, Karpati M, Li JZ, Yapici Z, Juhasz G, Lee JH, Klionsky DJ, Burmeister M.
Kim M, et al.
Elife. 2016 Jan 26;5:e12245. doi: 10.7554/eLife.12245.
Elife. 2016.
PMID: 26812546
Free PMC article.
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