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Acta Cytol. 1998 Nov-Dec;42(6):1441-3.

Macrofollicular variant of papillary thyroid carcinoma. Report of a case with fine needle aspiration biopsy findings.

Author information

1
Department of Pathology, Kawasaki Medical School, Kurashiki, Japan. hirokawa@med.kawasaki-m.ac.jp

Abstract

BACKGROUND:

Macrofollicular variant of papillary thyroid carcinoma is defined as a combination of numerous macrofollicles occupying 50% of the tumor and foci of the conventional follicular variant of papillary carcinoma. To the best of our knowledge, there have been no English-language reports on its cytologic findings.

CASE:

A fine needle aspiration specimen from a mass of the thyroid in a 59-year-old female showed a large collection of dense, inspissated colloid and a few sheets of tumor cells with nuclei characteristic of papillary carcinoma. There were no three-dimensional, branching papillae with fibrovascular cores.

CONCLUSION:

Although macrofollicular variant of papillary carcinoma is very rare, fine needle aspiration cytology may contribute to its correct diagnosis.

PMID:
9850657
DOI:
10.1159/000332182
[Indexed for MEDLINE]

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