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J Nat Prod. 1998 Nov;61(11):1386-7.

Inhibition of cAMP-phosphodiesterase by biflavones of Ginkgo biloba in rat adipose tissue.

Author information

1
Institute of Pharmacological Sciences, Faculty of Pharmacy, Via Balzaretti 9, 20133 Milan, Italy.

Abstract

This work compares the inhibition of cAMP-phosphodiesterase in rat adipose tissue by a mixture of Ginkgo biloba biflavones with the effect of individual dimeric flavonoids. The degree of enzyme inhibition by G. biloba biflavones was amentoflavone > bilobetin > sequoiaflavone > ginkgetin = isoginkgetin. Sciadopitysin was almost inactive.

PMID:
9834158
DOI:
10.1021/np970569m
[Indexed for MEDLINE]

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